We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Type C1 radical hysterectomy in advanced squamous cell carcinoma of the cervix postdefinitive concurrent chemoradiation: An argument.
- Authors
Sundaram, Gouthaman; Kothari, Snehalatha; Voleti, Sri; Krishna, Vijay; Bose, Jagadesh; Sundaram, Gouthaman Shanmuga; Voleti, Sri Karthik; Bose, Jagadesh Chandra
- Abstract
<bold>Aims: </bold>This study aimed to evaluate the feasibility and outcomes of patients with advanced cervical cancer treated with definitive concurrent chemoradiotherapy followed by Type C 1 nerve-sparing radical hysterectomy.<bold>Settings and Design: </bold>This is a prospective study to assess the feasibility of Type C 1 nerve-sparing radical hysterectomy postdefinitive chemoradiation in advanced carcinoma cervix.<bold>Subjects and Methods: </bold>We analyzed 25 patients with cervical cancer evaluated and treated with concurrent chemoradiation followed by surgery. Twenty patients underwent Type C 1 nerve-sparing radical hysterectomy by open surgery and five patients by laparoscopic approach. Postoperative morbidity and pathology were analyzed.<bold>Statistical Analysis Used: </bold>Analysis of the outcomes was done by arithmetical calculations.<bold>Results: </bold>Eight patients (32%) had persistent residual disease after definitive chemoradiation followed by surgery. Rest of the patients had pathological complete response. Two patients (8%) had node-positive disease. None of the patients in the laparoscopic group had bladder morbidity. One patient in the laparoscopic group had persistent vaginal discharge.<bold>Conclusions: </bold>Type C1 nerve-sparing radical hysterectomy is technically feasible with minimal morbidity following definitive chemoradiation in advanced squamous cell carcinoma of the cervix.
- Subjects
SQUAMOUS cell carcinoma; HYSTERECTOMY; CANCER patients; CHEMORADIOTHERAPY; VAGINAL discharge; CERVICAL cancer; CERVIX uteri surgery; CERVIX uteri tumors; TREATMENT effectiveness; LONGITUDINAL method; CERVIX uteri; ARTHRITIS Impact Measurement Scales
- Publication
Journal of Cancer Research & Therapeutics, 2022, Vol 18, Issue 6, p1559
- ISSN
0973-1482
- Publication type
journal article
- DOI
10.4103/jcrt.JCRT_557_20