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- Title
2-(2-Phenylethyl)chromone Derivatives of Agarwood Originating from Gyrinops salicifolia.
- Authors
Hang Shao; Wen-Li Mei; Wen-Hua Dong; Cui-Juan Gai; Wei Li; Guo-Peng Zhu; Hao-Fu Dai
- Abstract
Three new 2-(2-phenylethyl)chromone derivatives (1-3) and a new 2-(2-phenylethenyl)chromone derivative (4), together with two known 2-(2-phenylethyl)chromone derivatives (5-6), were isolated from agarwood originating from Gyrinops salicifolia Ridl. The structures of compounds 1-4 were elucidated by comprehensive spectroscopic techniques (UV, IR, 1D and 2D-NMR) and MS analysis, as well as by comparison with the literature. Compounds 1, 2, and 5 showed moderate cytotoxicity against human tumor K562, BEL-7402, and SGC-7901 cell lines with IC50 values of 5.76 to 20.1 µM.
- Subjects
CHROMONES; CHEMICAL derivatives; AGARWOOD (Wood); GYRINOPS; CELL-mediated cytotoxicity; CELL lines
- Publication
Molecules, 2016, Vol 21, Issue 10, p1313
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules21101313