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Characterization of Six in vitro Reactions Mediated by Human Cytochrome P450: Application to the Testing of Cytochrome P450-Directed Antibodies.
- Published in:
- Pharmacology, 1996, v. 52, n. 2, p. 125, doi. 10.1159/000139376
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- Publication type:
- Article
Alprazolam Metabolism in vitro: Studies of Human, Monkey, Mouse, and Rat Liver Microsomes.
- Published in:
- Pharmacology, 1993, v. 47, n. 4, p. 268, doi. 10.1159/000139107
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- Publication type:
- Article
Mechanism of cytochrome P450-3A inhibition by ketoconazole.
- Published in:
- Journal of Pharmacy & Pharmacology, 2011, v. 63, n. 2, p. 214, doi. 10.1111/j.2042-7158.2010.01202.x
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- Publication type:
- Article
Induction of P-glycoprotein expression and activity by ritonavir in bovine brain microvessel endothelial cells.
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- Journal of Pharmacy & Pharmacology, 2007, v. 59, n. 7, p. 947, doi. 10.1211/jpp.59.7.0006
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- Publication type:
- Article
Ethanol inhibits in-vitro metabolism of nifedipine, triazolam and testosterone in human liver microsomes.
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- Journal of Pharmacy & Pharmacology, 2004, v. 56, n. 8, p. 963
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- Publication type:
- Article
Inhibition of human cytochromes P450 by components of Ginkgo biloba.
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- Journal of Pharmacy & Pharmacology, 2004, v. 56, n. 8, p. 1039
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- Publication type:
- Article
Phenacetin and chlorzoxazone biotransformation in aging male Fischer 344 rats.
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- Journal of Pharmacy & Pharmacology, 2004, v. 56, n. 6, p. 819
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- Publication type:
- Article
Phenacetin and chlorzoxazone biotransformation in aging male Fischer 344 rats.
- Published in:
- Journal of Pharmacy & Pharmacology, 2004, v. 56, n. 6, p. 819
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- Publication type:
- Article
Effect of bupropion on CYP2B6 and CYP3A4 catalytic activity, immunoreactive protein and mRNA levels in primary human hepatocytes: comparison with rifampicin.
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- Journal of Pharmacy & Pharmacology, 2003, v. 55, n. 9, p. 1229
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- Publication type:
- Article
Apparent mechanism-based inhibition of human CYP3A in-vitro by lopinavir.
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- Journal of Pharmacy & Pharmacology, 2003, v. 55, n. 3, p. 381, doi. 10.1211/002235702739
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- Publication type:
- Article
Effect of Food on the Bioavailability and Tolerability of the JAK2-Selective Inhibitor Fedratinib (SAR302503): Results From Two Phase I Studies in Healthy Volunteers.
- Published in:
- Clinical Pharmacology in Drug Development, 2015, v. 4, n. 4, p. 315, doi. 10.1002/cpdd.161
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- Publication type:
- Article
Antipyrine Kinetics in Patients with Primary Biliary Cirrhosis.
- Published in:
- 1993
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- Publication type:
- Other
Validity of Self-Reports of Caffeine Use.
- Published in:
- 1991
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- Publication type:
- Other
Pharmacokinetics, safety and tolerability of mipomersen in healthy Japanese volunteers and comparison with Western subjects.
- Published in:
- International Journal of Clinical Pharmacology & Therapeutics, 2014, v. 52, n. 4, p. 314, doi. 10.5414/CP201975
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- Publication type:
- Article
Effect of zolpidem on human Cytochrome P450 activity, and on transport mediated by P-glycoprotein.
- Published in:
- Biopharmaceutics & Drug Disposition, 2002, v. 23, n. 9, p. 361, doi. 10.1002/bdd.329
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- Publication type:
- Article
Evaluation of Supermix<sup>TM</sup> as an in vitro model of human liver microsomal drug metabolism.
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- Biopharmaceutics & Drug Disposition, 2002, v. 23, n. 5, p. 183, doi. 10.1002/bdd.307
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- Publication type:
- Article
Inhibition of human cytochrome P450 isoforms in vitro by zafirlukast.
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- Biopharmaceutics & Drug Disposition, 1999, v. 20, n. 8, p. 385, doi. 10.1002/1099-081X(199911)20:8<385::AID-BDD203>3.0.CO;2-7
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- Publication type:
- Article
Biotransformation of Chlorzoxazone by Heptatic Microsomes from Humans and Ten Other Mammalian Species.
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- Biopharmaceutics & Drug Disposition, 1997, v. 18, n. 3, p. 213, doi. 10.1002/(SICI)1099-081X(199704)18:3<213::AID-BDD15>3.0.CO;2-0
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- Publication type:
- Article
Metabolism of Dextromethorphan in vitro: Involvement of Cytochromes P450 2D6 AND 3A3/4, with a Possible Role of 2E1.
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- Biopharmaceutics & Drug Disposition, 1997, v. 18, n. 3, p. 227, doi. 10.1002/(SICI)1099-081X(199704)18:3<227::AID-BDD18>3.0.CO;2-L
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- Publication type:
- Article
ALPRAZOLAM HYDROXYLATION BY MOUSE LIVER MICROSOMES IN VITRO: THE EFFECT OF AGE AND PHENOBARBITAL INDUCTION.
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- Biopharmaceutics & Drug Disposition, 1997, v. 18, n. 2, p. 139, doi. 10.1002/(SICI)1099-081X(199703)18:2<139::AID-BDD7>3.0.CO;2-Z
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- Publication type:
- Article
Inhibition of acetaminophen and lorazepam glucuronidation in vitro by probenecid.
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- Biopharmaceutics & Drug Disposition, 1993, v. 14, n. 2, p. 119, doi. 10.1002/bdd.2510140204
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- Publication type:
- Article
Effect of extended exposure to grapefruit juice on cytochrome P450 3A activity in humans: Comparison with ritonavir<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 2006, v. 79, n. 3, p. 243, doi. 10.1016/j.clpt.2005.11.009
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- Publication type:
- Article
Interaction of flurbiprofen with cranberry juice, grape juice, tea, and fluconazole: In vitro and clinical studies*.
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- Clinical Pharmacology & Therapeutics, 2006, v. 79, n. 1, p. 125, doi. 10.1016/j.clpt.2005.09.014
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- Publication type:
- Article
Genotype-phenotype associations of cytochrome P450 3A4 and 3A5 polymorphism with midazolam clearance in vivo.
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- Clinical Pharmacology & Therapeutics, 2005, v. 77, n. 5, p. 373
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- Publication type:
- Article
Age and gender effects on the pharmacokinetics and pharmacodynamics of triazolam, a cytochrome P450 3A substrate<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 2004, v. 76, n. 5, p. 467, doi. 10.1016/j.clpt.2004.07.009
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- Publication type:
- Article
Time course of recovery of cytochrome p450 3A function after single doses of grapefruit juice<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 2003, v. 74, n. 2, p. 121, doi. 10.1016/S0009-9236(03)00118-8
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- Publication type:
- Article
Alprazolam-ritonavir interaction: Implications for product labeling<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 2000, v. 67, n. 4, p. 335, doi. 10.1067/mcp.2000.105757
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- Publication type:
- Article
Differentiation of intestinal and hepatic cytochrome P450 3A activity with use of midazolam as an in vivo probe: Effect of ketoconazole<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 1999, v. 66, n. 5, p. 461, doi. 10.1016/S0009-9236(99)70009-3
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- Publication type:
- Article
The substrate-independence assumption of the relative activity factor (RAF) approach.
- Published in:
- Clinical Pharmacology & Therapeutics, 1999, v. 65, n. 2, p. 121, doi. 10.1016/S0009-9236(99)80016-2
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- Publication type:
- Article
Kinetic and dynamic interaction study of zolpidem with ketoconazole, itraconazole, and fluconazole<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 1998, v. 64, n. 6, p. 661, doi. 10.1016/S0009-9236(98)90057-1
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- Publication type:
- Article
Comparative kinetics and dynamics of zaleplon, zolpidem, and placebo<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 1998, v. 64, n. 5, p. 553, doi. 10.1016/S0009-9236(98)90139-4
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- Publication type:
- Article
Inhibition of triazolam clearance by macrolide antimicrobial agents: In vitro correlates and dynamic consequences<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 1998, v. 64, n. 3, p. 278, doi. 10.1016/S0009-9236(98)90176-X
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- Publication type:
- Article
Ketoconazole inhibition of triazolam and alprazolam clearance: Differential kinetic and dynamic consequences<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 1998, v. 64, n. 3, p. 237, doi. 10.1016/S0009-9236(98)90172-2
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- Publication type:
- Article
Molecular and Pharmacokinetic Evaluation of Rat Hepatic and Gastrointestinal Cytochrome P450 Induction by Tamoxifen.
- Published in:
- Pharmacology, 2001, v. 63, n. 4, p. 210, doi. 10.1159/000056136
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- Publication type:
- Article
Pharmacological profile of ALKS 7119, an investigational compound evaluated for the treatment of neuropsychiatric disorders, in healthy volunteers.
- Published in:
- British Journal of Clinical Pharmacology, 2022, v. 88, n. 6, p. 2909, doi. 10.1111/bcp.15229
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- Publication type:
- Article
Predicting interactions between conventional medications and botanical products on the basis of in vitro investigations.
- Published in:
- Molecular Nutrition & Food Research, 2008, v. 52, n. 7, p. 747, doi. 10.1002/mnfr.200700159
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- Publication type:
- Article
Relative contributions of CYP2C9 and 2C19 to phenytoin 4-hydroxylation in vitro: inhibition by sulfaphenazole, omeprazole, and ticlopidine.
- Published in:
- European Journal of Clinical Pharmacology, 2001, v. 57, n. 1, p. 31, doi. 10.1007/s002280100268
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- Publication type:
- Article
Fluvoxamine impairs single-dose caffeine clearance without altering caffeine pharmacodynamics.
- Published in:
- British Journal of Clinical Pharmacology, 2005, v. 60, n. 5, p. 486, doi. 10.1111/j.1365-2125.2005.02467.x
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- Publication type:
- Article
Pharmacokinetic properties of zolpidem in elderly and young adults: possible modulation by testosterone in men.
- Published in:
- British Journal of Clinical Pharmacology, 2003, v. 56, n. 3, p. 297, doi. 10.1046/j.0306-5251.2003.01852.x
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- Publication type:
- Article
Zolpidem metabolism in vitro: responsible cytochromes, chemical inhibitors, andin vivo correlations.
- Published in:
- British Journal of Clinical Pharmacology, 1999, v. 48, n. 1, doi. 10.1046/j.1365-2125.1999.00953.x
- By:
- Publication type:
- Article
Inhibition of CYP2C9 by selective serotonin reuptake inhibitors in vitro: studies of phenytoin p-hydroxylation.
- Published in:
- British Journal of Clinical Pharmacology, 1997, v. 44, n. 5, p. 495, doi. 10.1046/j.1365-2125.1997.00601.x
- By:
- Publication type:
- Article
Inhibition of cytochrome P450 by nefazodone in vitro: studies of dextromethorphan O- and N-demethylation.
- Published in:
- British Journal of Clinical Pharmacology, 1996, v. 41, n. 4, p. 339, doi. 10.1046/j.1365-2125.1996.30512.x
- By:
- Publication type:
- Article
The influence of age and sex on the clearance of cytochrome P450 3A substrates.
- Published in:
- 2005
- By:
- Publication type:
- journal article
A randomized, placebo-controlled study of the pharmacokinetics, pharmacodynamics, and tolerability of the oral JAK2 inhibitor fedratinib ( SAR302503) in healthy volunteers.
- Published in:
- Journal of Clinical Pharmacology, 2014, v. 54, n. 4, p. 415, doi. 10.1002/jcph.218
- By:
- Publication type:
- Article
Gender Has a Small but Statistically Significant Effect on Clearance of CYP3A Substrate Drugs.
- Published in:
- Journal of Clinical Pharmacology, 2008, v. 48, n. 11, p. 1350, doi. 10.1177/0091270008323754
- By:
- Publication type:
- Article
Human Pregnane X Receptor: Genetic Polymorphisms, Alternative mRNA Splice Variants, and Cytochrome P450 3A Metabolic Activity.
- Published in:
- Journal of Clinical Pharmacology, 2006, v. 46, n. 11, p. 1356, doi. 10.1177/0091270006292125
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- Publication type:
- Article
Updates for The Journal of Clinical Pharmacology.
- Published in:
- Journal of Clinical Pharmacology, 2006, v. 46, n. 7, p. 714, doi. 10.1177/0091270006290856
- By:
- Publication type:
- Article
Ritonavir Has Minimal Impact on the Pharmacokinetic Disposition of a Single Dose of Bupropion Administered to Human Volunteers.
- Published in:
- Journal of Clinical Pharmacology, 2006, v. 46, n. 5, p. 567, doi. 10.1177/0091270006286981
- By:
- Publication type:
- Article
Ginkgo biloba Does Not Alter Clearance of Flurbiprofen, a Cytochrome P450-2C9 Substrate.
- Published in:
- Journal of Clinical Pharmacology, 2006, v. 46, n. 2, p. 214, doi. 10.1177/0091270005283465
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- Publication type:
- Article
A Few Thoughts From the New Editor.
- Published in:
- Journal of Clinical Pharmacology, 2005, v. 45, n. 2, p. 126, doi. 10.1177/0091270004273509
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- Publication type:
- Article