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- Title
微/纳多级结构TiO<sub>2</sub>涂层的制备及生物学性能.
- Authors
顾静萍; 谢有桃; 黄利平; 贺延昌; 赵君; 郑学斌; 李红; 孙晋良
- Abstract
Micro/nano hybrid structured surface can improve their capability of encouraging early cell responses and rapid bone in-growth. The micro/nano hybrid structured TiO2 coatings were prepared by induction suspension plasma spraying (ISPS) using anatase TiO2 suspension as a feedstock. Their osteogenesis related cell behaviors were studied. Scanning transmission electron microscopy (SEM) results show that the coatings prepared by adjusting feed rate have typical micro/nano hybrid structures. Porosity of the coating increases with the increase of feed rate. The X-ray diffraction (XRD) results show that the coating is mainly composed of rutile with a small amount of anatase, and the content of rutile decreased with the increase of feed rate. This may be related to the high temperature process of plasma spraying, in which the anatase phase is transformed into a more stable rutile phase. The results of in vitro cell compatibility tests show that the micro/nano structured TiO2 coatings prepared with ISPS has higher protein adsorption, better osteoblasts spreading and higher expression of alkaline phosphatase (ALP) activity and mineralization than atmospheric plasma sprayed coatings and polished titanium surfaces.
- Publication
Journal of Shanghai University / Shanghai Daxue Xuebao, 2018, Vol 24, Issue 1, p44
- ISSN
1007-2861
- Publication type
Article
- DOI
10.12066/j.issn.1007-2861.1921