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- Title
High-throughput live-cell imaging reveals differential inhibition of tumor cell proliferation by human fibroblasts.
- Authors
Flaberg, Emilie; Markasz, Laszlo; Petranyi, Gabor; Stuber, Gyorgy; Dicső, Ferenc; Alchihabi, Nidal; Oláh, Èva; Csízy, István; Józsa, Tamás; Andrén, Ove; Johansson, Jan-Erik; Andersson, Swen-Olof; Klein, George; Szekely, Laszlo
- Abstract
The article discusses a study that investigated the effect of human fibroblasts on the growth of tumor cells using a high-throughput multidimensional imaging system. The study focused on primary fibroblasts from pediatric and adult donors and six human tumor cell lines. Some of the tumor cell lines came from prostate and lung carcinomas. The study found that human fibroblasts inhibit the proliferation of tumor cells in varying degrees depending on their site of origin and the donor's age.
- Subjects
FIBROBLASTS; CELLS; CANCER cells; CELLULAR pathology; IMAGING systems
- Publication
International Journal of Cancer, 2011, Vol 128, Issue 12, p2793
- ISSN
0020-7136
- Publication type
Article
- DOI
10.1002/ijc.25612