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- Title
The Role of Gut Bacteriome in Asthma, Chronic Obstructive Pulmonary Disease and Obstructive Sleep Apnoea.
- Authors
Bikov, Andras; Dragonieri, Silvano; Csoma, Balazs; Mazzuca, Carmen; Finamore, Panaiotis; Rocchi, Giulia; Putignani, Lorenza; Guarino, Michele; Scarlata, Simone
- Abstract
The human body contains a very complex and dynamic ecosystem of bacteria. The bacteriome interacts with the host bi-directionally, and changes in either factor impact the entire system. It has long been known that chronic airway diseases are associated with disturbances in the lung bacteriome. However, less is known about the role of gut bacteriome in the most common respiratory diseases. Here, we aim to summarise the evidence concerning the role of the intestinal bacteriome in the pathogenesis and disease course of bronchial asthma, chronic obstructive pulmonary disease, and obstructive sleep apnea. Furthermore, we discuss the consequences of an altered gut bacteriome on the most common comorbidities of these lung diseases. Lastly, we also reflect on the therapeutic potential of influencing the gut microbiome to improve disease outcomes.
- Subjects
CHRONIC obstructive pulmonary disease; SLEEP apnea syndromes; BRONCHIAL diseases; LUNGS; ASTHMA; LUNG diseases; PREMATURE infants
- Publication
Microorganisms, 2022, Vol 10, Issue 12, p2457
- ISSN
2076-2607
- Publication type
Article
- DOI
10.3390/microorganisms10122457