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- Title
Dual-time-point FDG-PET/CT Imaging of Temporal Bone Chondroblastoma: A Report of Two Cases.
- Authors
Akira Toriihara; Atsunobu Tsunoda; Akira Takemoto; Kazunori Kubota; Youichi Machida; Ukihide Tateishi
- Abstract
Temporal bone chondroblastoma is an extremely rare benign bone tumor. We encountered two cases showing similar imaging findings on computed tomography (CT), magnetic resonance imaging (MRI), and dual-time-point 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET)/CT. In both cases, CT images revealed temporal bone defects and sclerotic changes around the tumor. Most parts of the tumor showed low signal intensity on T2-weighted MRI images and non-uniform enhancement on gadolinium contrastenhanced T1-weighted images. No increase in signal intensity was noted in diffusion-weighted images. Dual-time-point PET/CT showed markedly elevated 18F-FDG uptake, which increased from the early to delayed phase. Nevertheless, immunohistochemical analysis of the resected tumor tissue revealed weak expression of glucose transporter-1 and hexokinase II in both tumors. Temporal bone tumors, showing markedly elevated 18F-FDG uptake, which increases from the early to delayed phase on PET/CT images, may be diagnosed as malignant bone tumors. Therefore, the differential diagnosis should include chondroblastoma in combination with its characteristic findings on CT and MRI.
- Subjects
CHONDROBLASTOMA; TEMPORAL bone tumors; IMMUNOHISTOCHEMISTRY; MAGNETIC resonance imaging; FLUORODEOXYGLUCOSE F18; DIAGNOSIS
- Publication
Asia Oceania Journal of Nuclear Medicine & Biology, 2015, Vol 3, Issue 2, p120
- ISSN
2322-5718
- Publication type
Case Study