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- Title
Case Report. Osteomyelitis caused by high resistant Candida guilliermondii.
- Authors
Tietz; Czaika; Sterry; Tietz, Hans-Jürgen
- Abstract
We describe a case of a 57-year-old patient with osteomyelitis at a finger of his right hand caused by Candida guilliermondii. The strains isolated were highly resistant to fluconazole and itraconazole. Using the three methods, microdilution, agardilation and E-test, the highest minimum inhibitory concentrations (MICs) amounted to >256 μg ml-1 for fluconazole and >32 μg ml-1 for itraconazole. To our knowledge, this is the first time such high values have been described for C. guilliermondii. They correlated with the therapeutic non-response to a triazole therapy in our patient. The patient was cured by partial amputation of the affected finger.
- Subjects
OSTEOMYELITIS; CANDIDA
- Publication
Mycoses, 1999, Vol 42, Issue 9/10, p577
- ISSN
0933-7407
- Publication type
Article
- DOI
10.1046/j.1439-0507.1999.00497.x