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- Title
EXTENDED RELEASE FORMULATION: AN OVERVIEW.
- Authors
Patil, Latesh P.; Ghodake, Chaitanya A.; Pawar, Sunil P.; Rane, Bhushan R.; Gujarathi, Nayan A.
- Abstract
Recently, controlled release drug delivery has become the standards in the modern pharmaceutical design and intensive research has been undertaken in achieving much better drug product effectiveness, reliability and safety. Oral Extended release drug delivery medication will continue to account for the largest share of drug delivery systems. Hence, in this work to formulate tablets in order to avoid the first pass metabolism and increase the bioavailability. Hence in this work an attempt was made to formulate extended release system in order to achieve plasma concentration profile up to 24 hrs. The extended release formulations are the type of formulations which will improves the therapeutic index of drug concentration. These formulations make the drug available over extended time period after oral administration. The extended release product will optimize therapeutic effect and safety of a drug at the same time improving the patient convenience and compliance. Here an attempt was made to formulate the Delayed Drug release in to the systemic circulation. Which will give detailed information about the formulation and formulation requirements to develop the ideal Delayed drug release formulation.
- Subjects
DOSAGE forms of drugs; DRUG delivery systems; BIOAVAILABILITY; ORAL drug administration; DRUG efficacy
- Publication
Pharma Science Monitor, 2013, Vol 4, Issue 1, p3522
- ISSN
0976-9242
- Publication type
Article