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Genomic landscape of lymphatic malformations: a case series and response to the PI3Ka inhibitor alpelisib in an N-of-1 clinical trial.
Published in:
eLife, 2022, p. 1, doi. 10.7554/eLife.74510
By:
- Shaheen, Montaser F.;
- Tse, Julie Y.;
- Sokol, Ethan S.;
- Masterson, Margaret;
- Bansal, Pranshu;
- Rabinowitz, Ian;
- Tarleton, Christy A.;
- Dobroff, Andrey S.;
- Smith, Tracey L.;
- Bocklage, Thèrése J.;
- Mannakee, Brian K.;
- Gutenkunst, Ryan N.;
- Bischoff, Joyce;
- Ness, Scott A.;
- Riedlinger, Gregory M.;
- Groisberg, Roman;
- Pasqualini, Renata;
- Ganesan, Shridar;
- Arap, Wadih
Publication type:
Article
Clinically Advanced Pheochromocytomas and Paragangliomas: A Comprehensive Genomic Profiling Study.
Published in:
Cancers, 2021, v. 13, n. 13, p. 3312, doi. 10.3390/cancers13133312
By:
- Bratslavsky, Gennady;
- Sokol, Ethan S.;
- Daneshvar, Michael;
- Necchi, Andrea;
- Shapiro, Oleg;
- Jacob, Joseph;
- Liu, Nick;
- Sanford, Tom S.;
- Pinkhasov, Ruben;
- Goldberg, Hanan;
- Killian, Jonathan K.;
- Ramkissoon, Shakti;
- Severson, Eric A.;
- Huang, Richard S. P.;
- Danziger, Natalie;
- Mollapour, Mehdi;
- Ross, Jeffrey S.;
- Pacak, Karel
Publication type:
Article
Increased KRAS G12C Prevalence, High Tumor Mutational Burden, and Specific Mutational Signatures Are Associated With MUTYH Mutations: A Pan-Cancer Analysis.
Published in:
Oncologist, 2024, v. 29, n. 2, p. e213, doi. 10.1093/oncolo/oyad230
By:
- Disel, Umut;
- Sivakumar, Smruthy;
- Pham, Tim;
- Fleischmann, Zoe;
- Anu, R I;
- Sokol, Ethan S;
- Kurzrock, Razelle
Publication type:
Article
Variable Landscape of PD-L1 Expression in Breast Carcinoma as Detected by the DAKO 22C3 Immunohistochemistry Assay.
Published in:
Oncologist, 2023, v. 28, n. 4, p. 319, doi. 10.1093/oncolo/oyad025
By:
- Danziger, Natalie;
- Sokol, Ethan S;
- Graf, Ryon P;
- Hiemenz, Matthew C;
- Maule, Jake;
- Parimi, Vamsi;
- Palmieri, Carlo;
- Pusztai, Lajos;
- Ross, Jeffrey S;
- Huang, Richard S P
Publication type:
Article
Advanced Squamous Cell Carcinomas of the Pelvic and Perineal Region: A Comprehensive Genomic Profiling Study.
Published in:
Oncologist, 2022, v. 27, n. 12, p. 1016, doi. 10.1093/oncolo/oyac144
By:
- Necchi, Andrea;
- Spiess, Philippe E;
- Bandini, Marco;
- Basile, Giuseppe;
- Grivas, Petros;
- Bratslavsky, Gennady;
- Jacob, Joseph;
- Danziger, Natalie;
- Lin, Douglas;
- Decker, Brennan;
- Sokol, Ethan S;
- Huang, Richard S P;
- Kulkarni, Sanjay B;
- Ross, Jeffrey S
Publication type:
Article
Homologous Recombination Deficiency: Concepts, Definitions, and Assays.
Published in:
Oncologist, 2022, v. 27, n. 3, p. 167, doi. 10.1093/oncolo/oyab053
By:
- Stewart, Mark D;
- Vega, Diana Merino;
- Arend, Rebecca C;
- Baden, Jonathan F;
- Barbash, Olena;
- Beaubier, Nike;
- Collins, Grace;
- French, Tim;
- Ghahramani, Negar;
- Hinson, Patsy;
- Jelinic, Petar;
- Marton, Matthew J;
- McGregor, Kimberly;
- Parsons, Jerod;
- Ramamurthy, Lakshman;
- Sausen, Mark;
- Sokol, Ethan S;
- Stenzinger, Albrecht;
- Stires, Hillary;
- Timms, Kirsten M
Publication type:
Article
Comparative Genomic Analysis of Intrahepatic Cholangiocarcinoma: Biopsy Type, Ancestry, and Testing Patterns.
Published in:
Oncologist, 2021, v. 26, n. 9, p. 787, doi. 10.1002/onco.13844
By:
- Israel, Mason A.;
- Danziger, Natalie;
- McGregor, Kimberly A.;
- Murugesan, Karthikeyan;
- Gjoerup, Ole;
- Sokol, Ethan S.;
- Tukachinsky, Hanna;
- Kurzrock, Razelle;
- Kato, Shumei;
- Sicklick, Jason K.;
- Nimeiri, Halla S.;
- Oxnard, Geoffrey R.;
- Ross, Jeffrey S.
Publication type:
Article
Comprehensive Genomic Profiling of Carcinoma of Unknown Primary Origin: Retrospective Molecular Classification Considering the CUPISCO Study Design.
Published in:
Oncologist, 2021, v. 26, n. 3, p. e394, doi. 10.1002/onco.13597
By:
- Ross, Jeffrey S.;
- Sokol, Ethan S.;
- Moch, Holger;
- Mileshkin, Linda;
- Baciarello, Giulia;
- Losa, Ferran;
- Beringer, Andreas;
- Thomas, Marlene;
- Elvin, Julia A.;
- Ngo, Nhu;
- Jin, Dexter X.;
- Krämer, Alwin
Publication type:
Article
Tumor Mutational Burden as a Predictive Biomarker for Response to Immune Checkpoint Inhibitors: A Review of Current Evidence.
Published in:
Oncologist, 2020, v. 25, n. 1, p. e147, doi. 10.1634/theoncologist.2019-0244
By:
- Klempner, Samuel J.;
- Fabrizio, David;
- Bane, Shalmali;
- Reinhart, Marcia;
- Peoples, Tim;
- Ali, Siraj M.;
- Sokol, Ethan S.;
- Frampton, Garrett;
- Schrock, Alexa B.;
- Anhorn, Rachel;
- Reddy, Prasanth
Publication type:
Article
The Pan‐Cancer Landscape of Coamplification of the Tyrosine Kinases KIT, KDR, and PDGFRA.
Published in:
Oncologist, 2020, v. 25, n. 1, p. e39, doi. 10.1634/theoncologist.2018-0528
By:
- Disel, Umut;
- Madison, Russell;
- Abhishek, Kumar;
- Chung, Jon H.;
- Trabucco, Sally E.;
- Matos, Asli O.;
- Frampton, Garrett M.;
- Albacker, Lee A.;
- Reddy, Venkataprasanth;
- Karadurmus, Nuri;
- Benson, Adam;
- Webster, Jennifer;
- Paydas, Semra;
- Cabanillas, Ruben;
- Nangia, Chaitali;
- Ozturk, M.A.;
- Millis, Sherri Z.;
- Pal, Sumanta K.;
- Wilky, Breelyn;
- Sokol, Ethan S.
Publication type:
Article
Pan‐Cancer Analysis of CDK12 Loss‐of‐Function Alterations and Their Association with the Focal Tandem‐Duplicator Phenotype.
Published in:
Oncologist, 2019, v. 24, n. 12, p. 1526, doi. 10.1634/theoncologist.2019-0214
By:
- Sokol, Ethan S.;
- Pavlick, Dean;
- Frampton, Garrett M.;
- Ross, Jeffrey S.;
- Miller, Vincent A.;
- Ali, Siraj M.;
- Lotan, Tamara L.;
- Pardoll, Drew M.;
- Chung, Jon H.;
- Antonarakis, Emmanuel S.
Publication type:
Article
Functional characterization of SMARCA4 variants identified by targeted exome-sequencing of 131,668 cancer patients.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-19402-8
By:
- Fernando, Tharu M.;
- Piskol, Robert;
- Bainer, Russell;
- Sokol, Ethan S.;
- Trabucco, Sally E.;
- Zhang, Qing;
- Trinh, Huong;
- Maund, Sophia;
- Kschonsak, Marc;
- Chaudhuri, Subhra;
- Modrusan, Zora;
- Januario, Thomas;
- Yauch, Robert L.
Publication type:
Article
Ancestry-associated co-alteration landscape of KRAS and EGFR-altered non-squamous NSCLC.
Published in:
NPJ Precision Oncology, 2024, v. 8, n. 1, p. 1, doi. 10.1038/s41698-024-00644-4
By:
- Sisoudiya, Saumya D.;
- Houle, Armande Ang;
- Fernando, Tharu;
- Wilson, Timothy R.;
- Schutzman, Jennifer L.;
- Lee, Jessica;
- Schrock, Alexa;
- Sokol, Ethan S.;
- Sivakumar, Smruthy;
- Shi, Zhen;
- Pathria, Gaurav
Publication type:
Article
Comprehensive pan-cancer genomic landscape of KRAS altered cancers and real-world outcomes in solid tumors.
Published in:
NPJ Precision Oncology, 2022, v. 6, n. 1, p. 1, doi. 10.1038/s41698-022-00334-z
By:
- Lee, Jessica K.;
- Sivakumar, Smruthy;
- Schrock, Alexa B.;
- Madison, Russell;
- Fabrizio, David;
- Gjoerup, Ole;
- Ross, Jeffrey S.;
- Frampton, Garrett M.;
- Napalkov, Pavel;
- Montesion, Meagan;
- Schutzman, Jennifer L.;
- Ye, Xin;
- Hegde, Priti S.;
- Nagasaka, Misako;
- Oxnard, Geoffrey R.;
- Sokol, Ethan S.;
- Ou, Sai-Hong Ignatius;
- Shi, Zhen
Publication type:
Article
Tissue and liquid biopsy profiling reveal convergent tumor evolution and therapy evasion in breast cancer.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-35245-x
By:
- Sivakumar, Smruthy;
- Jin, Dexter X.;
- Tukachinsky, Hanna;
- Murugesan, Karthikeyan;
- McGregor, Kimberly;
- Danziger, Natalie;
- Pavlick, Dean;
- Gjoerup, Ole;
- Ross, Jeffrey S.;
- Harmon, Robert;
- Chung, Jon;
- Decker, Brennan;
- Dennis, Lucas;
- Frampton, Garrett M.;
- Molinero, Luciana;
- Oesterreich, Steffi;
- Venstrom, Jeffrey M.;
- Oxnard, Geoffrey R.;
- Hegde, Priti S.;
- Sokol, Ethan S.
Publication type:
Article
Novel somatic alterations in unicentric and idiopathic multicentric Castleman disease.
Published in:
European Journal of Haematology, 2021, v. 107, n. 6, p. 642, doi. 10.1111/ejh.13702
By:
- Goodman, Aaron M.;
- Jeong, Ah‐Reum;
- Phillips, Alexis;
- Wang, Huan‐You;
- Sokol, Ethan S.;
- Cohen, Philip R.;
- Sicklick, Jason;
- Fajgenbaum, David C.;
- Kurzrock, Razelle
Publication type:
Article
Growth of human breast tissues from patient cells in 3D hydrogel scaffolds.
Published in:
2016
By:
- Sokol, Ethan S.;
- Miller, Daniel H.;
- Breggia, Anne;
- Spencer, Kevin C.;
- Arendt, Lisa M.;
- Gupta, Piyush B.
Publication type:
journal article
The genomic landscape of metastatic breast cancer: Insights from 11,000 tumors.
Published in:
PLoS ONE, 2020, v. 15, n. 5, p. 1, doi. 10.1371/journal.pone.0231999
By:
- Rinaldi, Jacob;
- Sokol, Ethan S.;
- Hartmaier, Ryan J.;
- Trabucco, Sally E.;
- Frampton, Garrett M.;
- Goldberg, Michael E.;
- Albacker, Lee A.;
- Daemen, Anneleen;
- Manning, Gerard
Publication type:
Article
Genomic landscape of pleural and peritoneal mesothelioma tumours.
Published in:
2022
By:
- Hiltbrunner, Stefanie;
- Fleischmann, Zoe;
- Sokol, Ethan S.;
- Zoche, Martin;
- Felley-Bosco, Emanuela;
- Curioni-Fontecedro, Alessandra
Publication type:
journal article
Frequent inactivating mutations of the PBAF complex gene PBRM1 in meningioma with papillary features.
Published in:
Acta Neuropathologica, 2020, v. 140, n. 1, p. 89, doi. 10.1007/s00401-020-02161-7
By:
- Williams, Erik A.;
- Wakimoto, Hiroaki;
- Shankar, Ganesh M.;
- Barker II, Fred G.;
- Brastianos, Priscilla K.;
- Santagata, Sandro;
- Sokol, Ethan S.;
- Pavlick, Dean C.;
- Shah, Nikunj;
- Reddy, Abhinav;
- Venstrom, Jeffrey M.;
- Alexander, Brian M.;
- Ross, Jeffrey S.;
- Cahill, Daniel P.;
- Ramkissoon, Shakti H.;
- Juratli, Tareq A.
Publication type:
Article
Breast tissue regeneration is driven by cell-matrix interactions coordinating multi-lineage stem cell differentiation through DDR1.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-27401-6
By:
- Rauner, Gat;
- Jin, Dexter X.;
- Miller, Daniel H.;
- Gierahn, Todd M.;
- Li, Carman M.;
- Sokol, Ethan S.;
- Feng, Yu-Xiong;
- Mathis, Robert A.;
- Love, J. Christopher;
- Gupta, Piyush B.;
- Kuperwasser, Charlotte
Publication type:
Article
Contrasting genomic profiles from metastatic sites, primary tumors, and liquid biopsies of advanced prostate cancer.
Published in:
Cancer (0008543X), 2021, v. 127, n. 24, p. 4557, doi. 10.1002/cncr.33865
By:
- Necchi, Andrea;
- Cucchiara, Vito;
- Grivas, Petros;
- Bratslavsky, Gennady;
- Jacob, Joseph;
- Spiess, Philippe E.;
- Sokol, Ethan S.;
- Killian, Jonathan Keith;
- Lin, Douglas;
- Ramkissoon, Shakti;
- Huang, Richard S. P.;
- Madison, Russell W.;
- Venstrom, Jeffrey M.;
- Schrock, Alexa B.;
- Danziger, Natalie;
- Decker, Brennan;
- Gjoerup, Ole;
- Graf, Ryon P.;
- Oxnard, Geoffrey R.;
- Tukachinsky, Hanna
Publication type:
Article
Cancer-specific PERK signaling drives invasion and metastasis through CREB3L1.
Published in:
Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01052-y
By:
- Yu-Xiong Feng;
- Jin, Dexter X.;
- Sokol, Ethan S.;
- Reinhardt, Ferenc;
- Miller, Daniel H.;
- Gupta, Piyush B.
Publication type:
Article
De-Differentiation Confers Multidrug Resistance Via Noncanonical PERK-Nrf2 Signaling.
Published in:
PLoS Biology, 2014, v. 12, n. 9, p. 1, doi. 10.1371/journal.pbio.1001945
By:
- Del Vecchio, Catherine A.;
- Feng, Yuxiong;
- Sokol, Ethan S.;
- Tillman, Erik J.;
- Sanduja, Sandhya;
- Reinhardt, Ferenc;
- Gupta, Piyush B.
Publication type:
Article
Prevalence of targetable genomic alterations in young women with advanced breast cancer: a cross-sectional study.
Published in:
Breast Cancer Research & Treatment, 2024, v. 204, n. 1, p. 181, doi. 10.1007/s10549-023-07179-5
By:
- Blansky, Deanna;
- Ansari, Norin;
- Gao, Lucy;
- Sokol, Ethan S.;
- Sivakumar, Smruthy;
- Huang, Richard S.P.;
- Pelletier, Maureen;
- Levy, Mia;
- Pavlick, Dean;
- Danziger, Natalie;
- Ross, Jeffrey S;
- Lustberg, Maryam;
- Rozenblit, Mariya
Publication type:
Article
Prevalence of targetable genomic alterations in young women with advanced breast cancer: a cross-sectional study.
Published in:
Breast Cancer Research & Treatment, 2024, v. 203, n. 3, p. 181, doi. 10.1007/s10549-023-07179-5
By:
- Blansky, Deanna;
- Ansari, Norin;
- Gao, Lucy;
- Sokol, Ethan S.;
- Sivakumar, Smruthy;
- Huang, Richard S.P.;
- Pelletier, Maureen;
- Levy, Mia;
- Pavlick, Dean;
- Danziger, Natalie;
- Ross, Jeffrey S;
- Lustberg, Maryam;
- Rozenblit, Mariya
Publication type:
Article
FGFR4 overexpression and hotspot mutations in metastatic ER+ breast cancer are enriched in the lobular subtype.
Published in:
NPJ Breast Cancer, 2019, v. 5, n. 1, p. N.PAG, doi. 10.1038/s41523-019-0114-x
By:
- Levine, Kevin M.;
- Priedigkeit, Nolan;
- Basudan, Ahmed;
- Tasdemir, Nilgun;
- Sikora, Matthew J.;
- Sokol, Ethan S.;
- Hartmaier, Ryan J.;
- Ding, Kai;
- Ahmad, Nedah Z.;
- Watters, Rebecca J.;
- Weiss, Kurt R.;
- Blohmer, Jens-Uwe;
- Denkert, Carsten;
- Machleidt, Anna;
- Karsten, Maria M.;
- Boisen, Michelle M.;
- Elishaev, Esther;
- Lucas, Peter C.;
- Lee, Adrian V.;
- Oesterreich, Steffi
Publication type:
Article
The Molecular Landscape of Pancreatobiliary Cancers for Novel Targeted Therapies From Real-World Genomic Profiling.
Published in:
2022
By:
- Umemoto, Kumiko;
- Yamamoto, Hiroyuki;
- Oikawa, Ritsuko;
- Takeda, Hiroyuki;
- Doi, Ayako;
- Horie, Yoshiki;
- Arai, Hiroyuki;
- Ogura, Takashi;
- Mizukami, Takuro;
- Izawa, Naoki;
- Moore, Jay A;
- Sokol, Ethan S;
- Sunakawa, Yu
Publication type:
journal article
Predictive Biomarkers for Immune Checkpoint Inhibitors in Metastatic Breast Cancer.
Published in:
Cancer Medicine, 2021, v. 10, n. 1, p. 53, doi. 10.1002/cam4.3550
By:
- Sivapiragasam, Abirami;
- Ashok Kumar, Prashanth;
- Sokol, Ethan S.;
- Albacker, Lee A.;
- Killian, Jonathan K.;
- Ramkissoon, Shakti H.;
- Huang, Richard S. P.;
- Severson, Eric A.;
- Brown, Charlotte A.;
- Danziger, Natalie;
- McGregor, Kimberly;
- Ross, Jeffrey S.
Publication type:
Article
Case Report: Multiple Chromosomal Translocations Including Novel CIITA-CREBBP Fusion and Mutations in a Follicular Lymphoma.
Published in:
Frontiers in Oncology, 2021, v. 11, p. N.PAG, doi. 10.3389/fonc.2021.620435
By:
- Wang, Huan-You;
- Sokol, Ethan S.;
- Goodman, Aaron M.;
- Feldman, Andrew L.;
- Mulroney, Carolyn M.
Publication type:
Article
S100a4 upregulation in Pik3caH1047R;Trp53R270H;MMTV-Cre-driven mammary tumors promotes metastasis.
Published in:
2019
By:
- Yuan, Wenlin;
- Goldstein, Leonard D.;
- Durinck, Steffen;
- Chen, Ying-Jiun;
- Nguyen, Thong T.;
- Kljavin, Noelyn M.;
- Sokol, Ethan S.;
- Stawiski, Eric W.;
- Haley, Benjamin;
- Ziai, James;
- Modrusan, Zora;
- Seshagiri, Somasekar
Publication type:
journal article
NTRK gene fusions are detected in both secretory and non‐secretory breast cancers.
Published in:
Pathology International, 2022, v. 72, n. 3, p. 187, doi. 10.1111/pin.13204
By:
- Maund, Sophia L.;
- Sokol, Ethan S.;
- Ang Houle, Armande;
- Ross, Jeffrey S.;
- Wilson, Timothy R.
Publication type:
Article
Higher tumor mutational burden and PD-L1 expression correlate with shorter survival in hematologic malignancies.
Published in:
Therapeutic Advances in Medical Oncology, 2024, p. 1, doi. 10.1177/17588359241273053
By:
- Jeong, Ah-Reum;
- Trando, Aaron H.;
- Thomas, Sean D.;
- Riviere, Paul;
- Sakowski, Patrick J.;
- Sokol, Ethan S.;
- Goodman, Aaron M.;
- Kurzrock, Razelle
Publication type:
Article
The Molecular Landscape of Gastric Cancers for Novel Targeted Therapies from Real-World Genomic Profiling.
Published in:
Targeted Oncology, 2024, v. 19, n. 3, p. 459, doi. 10.1007/s11523-024-01052-1
By:
- Yamamoto, Hiroyuki;
- Arai, Hiroyuki;
- Oikawa, Ritsuko;
- Umemoto, Kumiko;
- Takeda, Hiroyuki;
- Mizukami, Takuro;
- Kubota, Yohei;
- Doi, Ayako;
- Horie, Yoshiki;
- Ogura, Takashi;
- Izawa, Naoki;
- Moore, Jay A.;
- Sokol, Ethan S.;
- Sunakawa, Yu
Publication type:
Article
Landscape of homologous recombination deficiencies in solid tumours: analyses of two independent genomic datasets.
Published in:
2022
By:
- Lai, Zhongwu;
- Brosnan, Matthew;
- Sokol, Ethan S.;
- Xie, Mingchao;
- Dry, Jonathan R.;
- Harrington, Elizabeth A.;
- Barrett, J. Carl;
- Hodgson, Darren
Publication type:
journal article
Multiple PIK3CA mutation clonality correlates with outcomes in taselisib + fulvestrant-treated ER+/HER2–, PIK3CA-mutated breast cancers.
Published in:
Genome Medicine, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13073-023-01181-8
By:
- Hutchinson, Katherine E.;
- Chen, Jessica W.;
- Savage, Heidi M.;
- Stout, Thomas J.;
- Schimmoller, Frauke;
- Cortés, Javier;
- Dent, Susan;
- Harbeck, Nadia;
- Jacot, William;
- Krop, Ian;
- Trabucco, Sally E.;
- Sivakumar, Smruthy;
- Sokol, Ethan S.;
- Wilson, Timothy R.
Publication type:
Article
Perturbation-Expression Analysis Identifies RUNX1 as a Regulator of Human Mammary Stem Cell Differentiation.
Published in:
PLoS Computational Biology, 2015, v. 11, n. 4, p. 1, doi. 10.1371/journal.pcbi.1004161
By:
- Sokol, Ethan S.;
- Sanduja, Sandhya;
- Jin, Dexter X.;
- Miller, Daniel H.;
- Mathis, Robert A.;
- Gupta, Piyush B.
Publication type:
Article

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