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- Title
Significance of Immature Platelet Fraction in Diagnosed Patients of the Immune Thrombocytopenic Purpura.
- Authors
Haider, Mohammad Shabih; Mahmood, Asad; Bozdar, Manzar; Zahir, Saima; Muzafar, Saadia; Bukhari, Maliha Batool
- Abstract
Objective: Determination of significance of immature platelet fraction (IPF%) in diagnosed patients of Immune thrombocytopenic purpura (ITP). Study Design: It was a cross-sectional study. Place and Study Duration: Haematology department, Armed forces Institute of Pathology (AFIP), Rawalpindi Pakistan June 2021 to December 2021. Methodology: Patients of all ages and genders diagnosed with ITP and platelets less than 100 x 109/L after a review of peripheral blood film were included in the study. Detailed history and examination were made, complete blood count (CBC) test was done on Sysmex XN-3000 automated haematology analyzer. Peripheral blood was stained with Leishman stain and examined under a microscope to rule out pseudo thrombocytopenia and the presence of abnormal cells and dysplasia. After adequate quality and control, the immature platelet fraction was performed on Sysmex XN 3000. Results: Seventy-two diagnosed cases of immune thrombocytopenic purpura were part of the study. The mean age of the patients was 21.00±14.50 years. 34 (48%) patients were males, and 38 (52%) were females. The mean platelet count was 49.40±24.60. Mean IPF was 17.90±9.50 per microliter. Immature platelet fraction (IPF%) was raised in all the patients with immune thrombocytopenic purpura, confirming our hypothesis that IPF% was an independent predictor for the detection of ITP. Conclusion: Immature platelet fraction is a unique parameter that can pick patients having thrombocytopenia due to peripheral destruction, including immune thrombocytopenic purpura.
- Subjects
RAWALPINDI (Pakistan); PAKISTAN; IDIOPATHIC thrombocytopenic purpura; BLOOD platelets; BLOOD cell count; PLATELET count; BLOODSTAINS; HEMATOLOGY
- Publication
Pakistan Armed Forces Medical Journal, 2022, Vol 72, Issue 4, p1420
- ISSN
0030-9648
- Publication type
Abstract
- DOI
10.51253/pafmj.v72i4.8376