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- Title
Computed Tomography Imaging Assessment of the Effect of Vancomycin Paste on Poststernotomy Healing.
- Authors
Basha, Mohammad Abd Alkhalik; Shemais, Dina Said; Abdelwahed, Essam Saad; Elfwakhry, Rabab Mahmoud; Zeid, Ayman Fathy; Abdalla, Ahmed A El-Hamid M; Aly, Sameh Abdelaziz; Abdelrahman, Dalia Said; Elshenawy, Anwar A; Mansour, Waleed; Elbanna, Khaled Ahmed Ahmed; El Tahlawi, Mohammad; Elnahal, Nezar
- Abstract
Purpose: To assess vancomycin paste effect on poststernotomy healing in high-risk coronary artery bypass grafting (CABG) patients compared to bone wax using the 6-point computed tomography (CT) score. Additionally assessed the reliability of this score and its relationship to the occurrence of infection. Patients and Methods: A prospective comparative analysis included 126 high-risk CABG patients. The patients were randomly assigned into bone wax or vancomycin paste for sternal haemostasis. All patients were submitted to CT examinations 6-months postoperative. Two radiologists independently reviewed all CT scans to assess sternal healing using the 6-point CT score. The CT healing score of the two groups was compared. The kappa statistics were used to calculate the inter-reader agreement (IRA) of the 6-point CT score. Results: The final analysis included 61 patients in each group. The main CT score for sternal healing was 3.9± 0.4 in the vancomycin group and 3.3± 0.8 in the bone wax group. Patients in the vancomycin group had a higher statistically significant improvement in CT healing score than those in the bone wax group (p< 0.001). There was no statistically significant relationship (p = 0.79) between the occurrence of infection and the 6-point CT score in the vancomycin group. The overall IRA of the 6-point CT score was good in two groups (κ = 0.79 in the vancomycin group and = 0.78 in the bone wax group). Conclusion: Vancomycin paste had a better CT healing score and can be used as a sternal haemostatic material instead of bone wax. The 6-point CT healing score is a reliable diagnostic tool for evaluating sternal healing.
- Subjects
COMPUTED tomography; CORONARY artery bypass; HEALING; VANCOMYCIN
- Publication
International Journal of General Medicine, 2021, Vol 14, p9287
- ISSN
1178-7074
- Publication type
Article
- DOI
10.2147/IJGM.S343124