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- Title
Patients with chronic rhinosinusitis and simultaneous bronchial asthma suffer from significant extraesophageal reflux.
- Authors
Zeleník, Karol; Matoušek, Petr; Formánek, Martin; Urban, Ondřej; Komínek, Pavel
- Abstract
Background The aim of this study was to determine the severity of extraesophageal reflux (EER) in patients with various degrees of chronic rhinosinusitis (CRS), and particularly in patients with simultaneous bronchial asthma. Methods Patients with different severity of CRS were invited to participate in the study. Group I consisted of patients with CRS without nasal polyps or bronchial asthma; group II consisted of patients with CRS with nasal polyps but without bronchial asthma; group III consisted of patients with CRS with nasal polyps and bronchial asthma. The age, gender, Reflux Symptom Index, severity of EER evaluated using the Restech system, and number of previous functional endoscopic sinus surgeries (FESSs) were compared between groups. Results A total of 90 patients (30 in each group) were recruited for the study. Pathological EER was significantly often present in group III when compared with group I and group II in all parameters analyzed (RYAN score, number of EER episodes, total percentage of time below pH 5.5). Furthermore, patients from group III had undergone more surgeries in the past. Conclusion Patients with CRS with nasal polyps and simultaneous bronchial asthma suffer from significant EER. Antireflux therapy can be recommended for these patients. However, the effect has to be confirmed in further studies.
- Subjects
SINUSITIS; GASTROESOPHAGEAL reflux; ASTHMATICS; SYMPTOMS; ENDOSCOPIC surgery; PATIENTS
- Publication
International Forum of Allergy & Rhinology, 2015, Vol 5, Issue 10, p944
- ISSN
2042-6976
- Publication type
Article
- DOI
10.1002/alr.21560