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- Title
Antipseudomonal activity of total extract of the orange jasmine (Murraya paniculata [L.] Jack.) leaves.
- Authors
Fitri Kusuma, Sri Agung; Arifin, Junaedi; Herawati, Irma Erika
- Abstract
The aim of this study was to investigate the antipseudomonal activity of total extract of the orange jasmine (Murraya paniculata [L.] Jack.) leaves. Materials and Methods: Antipseudomonal activity was performed using the agar diffusion method with total extracts of leaves in different concentrations. As comparison, 2% of neomycin sulfate was used as antibiotic standard. The minimum inhibitory concentration (MIC) value of the extract was assayed using the macrodilution method. Meanwhile, the minimum bactericidal concentration (MBC) was determined by subculturing the MIC result onto the surface of agar medium. Results and Discussion: The result indicated that total M. paniculata extract was effective against Pseudomonas aeruginosa and significantly inhibited its growth in lower MIC and MBC value in the range of 0.1562‑0.3125% w/v. Conclusion: Our findings showed that M. paniculata leaf components have significant antipseudomonal activity and having potentials as new sources of effective antibacterial in healing of P. aeruginosa infections.
- Subjects
ANDROGRAPHIS paniculata; PSEUDOMONAS aeruginosa infections; JASMINE; EXTRACTS; PSEUDOMONAS aeruginosa
- Publication
Drug Invention Today, 2019, Vol 11, Issue 6, p1277
- ISSN
0975-7619
- Publication type
Article