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- Title
Internal Organization of Plasma Membranes during the Acantholytic Process. A Freeze-Fracture Study.
- Authors
Caputo, R.; Innocenti, M.; Gasparini, G.
- Abstract
The internal organization of plasma membranes was studied in seven subjects with pemphigus vulgaris and in one subject with familial pemphigus using the freeze-fracture technique. The results obtained seem to suggest that the acantholytic process is produced in a similar fashion whatever the pathogenic agent and that desmosomes represent the "target" membrane specializations in the acantholytic phenomena. The reduction and eventual disappearance of desmosomal particle aggregations is seemingly accompanied by an increase in gap junctions.
- Subjects
CELL membranes; PEMPHIGUS; FREEZE fracturing; BIOLOGICAL membranes; PATHOGENIC microorganisms; BONE fractures
- Publication
Journal of Cutaneous Pathology, 1980, Vol 7, Issue 2, p61
- ISSN
0303-6987
- Publication type
Article
- DOI
10.1111/j.1600-0560.1980.tb01184.x