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- Title
Editorial: Endocrine regulation of aging: impacts of humoral factors and circulating mediators.
- Authors
Petersen, Benjamin; Negri, Sharon; Milan, Madison; Reyff, Zeke; Ballard, Cade; Ihuoma, Jennifer; Ungvari, Zoltan; Tarantini, Stefano
- Abstract
This editorial published in the journal Frontiers in Endocrinology explores the connection between endocrine regulation and aging. It compiles research articles that investigate the role of hormonal and circulating factors in influencing the aging process. The document includes summaries of specific studies that examine various aspects of aging, such as NAD+ levels, metabolite levels and age-induced kidney dysfunction, FSH levels and the risk of developing rheumatoid arthritis, and the role of the somatotropic axis in vascular aging and cognitive impairment. The editorial also discusses the use of animal models to study the effects of PACAP deficiency on age-related degenerative signs and the relationship between circulating galectin-3 and frailty in elderly patients. The papers collectively provide insights into the mechanisms of aging and potential interventions.
- Subjects
ENDOCRINE system; PITUITARY adenylate cyclase activating polypeptide; AGING; OVARIAN follicle; SOMATOMEDIN C
- Publication
Frontiers in Endocrinology, 2024, p1
- ISSN
1664-2392
- Publication type
Article
- DOI
10.3389/fendo.2024.1387435