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- Title
Functional MRI Signal Complexity Analysis Using Sample Entropy.
- Authors
Nezafati, Maysam; Temmar, Hisham; Keilholz, Shella D.
- Abstract
Resting-state functional magnetic resonance imaging (rs-fMRI) is an immensely powerful method in neuroscience that uses the blood oxygenation level-dependent (BOLD) signal to record and analyze neural activity in the brain. We examined the complexity of brain activity acquired by rs-fMRI to determine whether it exhibits variation across brain regions. In this study the complexity of regional brain activity was analyzed by calculating the sample entropy of 200 whole-brain BOLD volumes as well as of distinct brain networks, cortical regions, and subcortical regions of these brain volumes. It can be seen that different brain regions and networks exhibit distinctly different levels of entropy/complexity, and that entropy in the brain significantly differs between brains at rest and during task performance.
- Subjects
FUNCTIONAL magnetic resonance imaging; ENTROPY (Information theory)
- Publication
Frontiers in Neuroscience, 2020, Vol 14, p1
- ISSN
1662-4548
- Publication type
Article
- DOI
10.3389/fnins.2020.00700