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Effective posttransplant antitumor immunity is associated with TLR-stimulating nucleic acid-immunoglobulin complexes in humans.
Published in:
2011
By:
- Lin, Yun;
- Zhang, Li;
- Cai, Ann X;
- Lee, Mark;
- Zhang, Wandi;
- Neuberg, Donna;
- Canning, Christine M;
- Soiffer, Robert J;
- Alyea, Edwin P;
- Ritz, Jerome;
- Hacohen, Nir;
- Means, Terry K;
- Wu, Catherine J
Publication type:
journal article
Article amendments.
Published in:
2011
Publication type:
Correction Notice
A composite MyD88/CD40 switch synergistically activates mouse and human dendritic cells for enhanced antitumor efficacy.
Published in:
2011
By:
- Narayanan, Priyadharshini;
- Lapteva, Natalia;
- Seethammagari, Mamatha;
- Levitt, Jonathan M.;
- Slawin, Kevin M.;
- Spencer, David M.
Publication type:
journal article
Loss of intestinal core 1-derived O-glycans causes spontaneous colitis in mice.
Published in:
2011
By:
- Fu, Jianxin;
- Wei, Bo;
- Wen, Tao;
- Johansson, Malin E V;
- Liu, Xiaowei;
- Bradford, Emily;
- Thomsson, Kristina A;
- McGee, Samuel;
- Mansour, Lilah;
- Tong, Maomeng;
- McDaniel, J Michael;
- Sferra, Thomas J;
- Turner, Jerrold R;
- Chen, Hong;
- Hansson, Gunnar C;
- Braun, Jonathan;
- Xia, Lijun
Publication type:
journal article
IL-2 induces a WAVE2-dependent pathway for actin reorganization that enables WASp-independent human NK cell function.
Published in:
2011
By:
- Orange, Jordan S.;
- Roy-Ghanta, Sumita;
- Mace, Emily M.;
- Maru, Saumya;
- Rak, Gregory O.;
- Sanborn, Ken B.;
- Fasth, Anders;
- Saltzman, Rushani;
- Paisley, Allison;
- Monaco-Shawver, Linda;
- Banerjee, Pinaki P.;
- Pandey, Rahul;
- Rak, Gregory D;
- Sanborn, Keri B
Publication type:
journal article
Impaired thymic tolerance to α-myosin directs autoimmunity to the heart in mice and humans.
Published in:
2011
By:
- Lv, Huijuan;
- Havari, Evis;
- Pinto, Sheena;
- Gottumukkala, Raju V S R K;
- Cornivelli, Lizbeth;
- Raddassi, Khadir;
- Matsui, Takashi;
- Rosenzweig, Anthony;
- Bronson, Roderick T;
- Smith, Ross;
- Fletcher, Anne L;
- Turley, Shannon J;
- Wucherpfennig, Kai;
- Kyewski, Bruno;
- Lipes, Myra A
Publication type:
journal article
Dysregulated brain creatine kinase is associated with hearing impairment in mouse models of Huntington disease.
Published in:
Journal of Clinical Investigation, 2011, v. 121, n. 4, p. 1519, doi. 10.1172/JCI43220
By:
- Yow-Sien Lin;
- Chiung-Mei Chen;
- Bing-wen Soong;
- Yih-Ru Wu;
- Hui-Mei Chen;
- Wen-Ying Yeh;
- Dai-Rong Wu;
- Yi-Jun Lin;
- Paul Wai-Fung Poon;
- Mei-Ling Cheng;
- Chih-Hung Wang;
- Yijuang Chern
Publication type:
Article
The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice.
Published in:
Journal of Clinical Investigation, 2011, v. 121, n. 4, p. 1373, doi. 10.1172/JCI42579
By:
- Yanan Yang;
- Young-Ho Ahn;
- Gibbons, Don L.;
- Vi Zang;
- Wei Lin;
- Thilaganathan, Nishan;
- Alvarez, Cristina A.;
- Moreira, Daniel C.;
- Creighton, Chad J.;
- Gregory, Philip A.;
- Goodall, Gregory J.;
- Kurie, Jonathan M.
Publication type:
Article
CXCL1 and its receptor, CXCR2, mediate murine sickle cell vaso-occlusion during hemolytic transfusion reactions.
Published in:
Journal of Clinical Investigation, 2011, v. 121, n. 4, p. 1397, doi. 10.1172/JCI45336
By:
- Jung-Eun Jang;
- Hod, Eldad A.;
- Spitalnik, Steven L.;
- Frenette, Paul S.
Publication type:
Article
Loss of intestinal core 1--derived O-glycans causes spontaneous colitis in mice.
Published in:
Journal of Clinical Investigation, 2011, v. 121, n. 4, p. 1657, doi. 10.1172/JCI45538
By:
- Jianxin Fu;
- Bo Wei;
- Tao Wen;
- Johansson, Malm E. V.;
- Xiaowei Liu;
- Bradford, Emily;
- Thomsson, Kristina A.;
- McGee, Samuel;
- Mansour, Lilah;
- Maomeng Tong;
- McDaniel, J. Michael;
- Sferra, Thomas J.;
- Turner, Jerrold A.;
- Hong Chen;
- Hansson, Gunnar C.;
- Braun, Jonathan;
- Lijun Xia
Publication type:
Article
Nitrite-generated NO circumvents dysregulated arginine/NOS signaling to protect against intimal hyperplasia in Sprague-Dawley rats.
Published in:
2011
By:
- Alef, Matthew J.;
- Vallabhaneni, Raghuveer;
- Carchman, Evie;
- Morris Jr., Sidney M.;
- Sruti Shiva;
- Yinna Wang;
- Kelley, Eric E.;
- Tarpey, Margaret M.;
- Gladwin, Mark T.;
- Tzeng, Edith;
- Zuckerbraun, Brian S.;
- Morris, Sidney M Jr;
- Shiva, Sruti;
- Wang, Yinna
Publication type:
journal article
PML-RARA can increase hematopoietic self-renewal without causing a myeloproliferative disease in mice.
Published in:
2011
By:
- Welch, John S.;
- Wenlin Yuan;
- Ley, Timothy J.;
- Yuan, Wenlin
Publication type:
journal article
Tie1 attenuation reduces murine atherosclerosis in a dose-dependent and shear stress-specific manner.
Published in:
Journal of Clinical Investigation, 2011, v. 121, n. 4, p. 1624, doi. 10.1172/JCI42040
By:
- Kel Vin Woo;
- Xianghu Qu;
- Babaev, Vladimir R.;
- Linton, MacRae F.;
- Guzman, Raul J.;
- Fazio, Sergio;
- Baldwin, H. Scott
Publication type:
Article
Peripheral calcium-permeable AMPA receptors regulate chronic inflammatory pain in mice.
Published in:
2011
By:
- Gangadharan, Vijayan;
- Rui Wang;
- Ulzhäfer, Bettina;
- Ceng Luo;
- Bardoni, Rita;
- Bali, Kiran Kumar;
- Agarwal, Nitin;
- Tegeder, Irmgard;
- Hildebrandt, Ulirich;
- Nagy, Gergely G.;
- Todd, Andrew J.;
- Ghirri, Alessia;
- Häussler, Annette;
- Sprengel, Rolf;
- Seeburg, Peter H.;
- MacDermott, Amy B.;
- Lewin, Gary R.;
- Kuner, Rohini;
- Wang, Rui;
- Ulzhöfer, Bettina
Publication type:
journal article
Single-cell Tsc1 knockout during corticogenesis generates tuber-like lesions and reduces seizure threshold in mice.
Published in:
2011
By:
- Feliciano, David M.;
- Su, Tiffany;
- Lopez, Jean;
- Platel, Jean-Claude;
- Bordey, Angelique;
- Bordey, Angélique
Publication type:
journal article
A Tbx1-Six1/Eya1-Fgf8 genetic pathway controls mammalian cardiovascular and craniofacial morphogenesis.
Published in:
Journal of Clinical Investigation, 2011, v. 121, n. 4, p. 1585, doi. 10.1172/JCI44630
By:
- Chaoshe Guo;
- Ye Sun;
- Bin Zhou;
- Adam, Rosalyn M.;
- Xiaokun Li;
- Pu, William T.;
- Morrow, Bernice E.;
- Moon, Anne;
- Xue Li
Publication type:
Article
Effective posttransplant antitumor immunity is associated with TLR-stimulating nucleic acid- immunoglobulin complexes in humans.
Published in:
Journal of Clinical Investigation, 2011, v. 121, n. 4, p. 1574, doi. 10.1172/JCI44581
By:
- Yun Lin;
- Li Zhang;
- Cai, Ann X.;
- Lee, Mark;
- Wandi Zhang;
- Neuberg, Donna;
- Canning, Christine M.;
- Soiffer, Robert J.;
- Alyea, Edwin P.;
- Ritz, Jerome;
- Hacohen, Nir;
- Means, Terry K.;
- Wu, Catherine J.
Publication type:
Article
Impaired thymic tolerance to α-myosin directs autoimmunity to the heart in mice and humans.
Published in:
Journal of Clinical Investigation, 2011, v. 121, n. 4, p. 1561, doi. 10.1172/JCI44583
By:
- Hui Juan Lv;
- Havari, Evis;
- Pinto, Sheena;
- Gottumukkala, Raju V. S. R. K.;
- Cornivelli, Lizbeth;
- Raddassi, Khadir;
- Matsui, Takashi;
- Rosenzweig, Anthony;
- Bronson, Roderick T.;
- Smith, Ross;
- Fletcher, Anne L.;
- Turley, Shannon J.;
- Kai Wucherpfennig;
- Kyewski, Bruno;
- Lipes, Myra A.
Publication type:
Article
CD4+ T cells from elite controllers resist HIV-1 infection by selective upregulation of p21.
Published in:
Journal of Clinical Investigation, 2011, v. 121, n. 4, p. 1549, doi. 10.1172/JCI44539
By:
- Huabiao Chen;
- Chun Li;
- Jinghe Huang;
- Thai Cung;
- Seiss, Katherine;
- Beamon, Jill;
- Carrington, Mary F.;
- Porter, Lindsay C.;
- Burke, Patrick S.;
- Yu Yang;
- Ryan, Bethany J.;
- Ruiwu Liu;
- Weiss, Robert H.;
- Pereyra, Florencia;
- Cress, William D.;
- Brass, Abraham L.;
- Rosenberg, Eric S.;
- Walker, Bruce D.;
- Yu, Xu G.;
- Lichterfeld, Mathias
Publication type:
Article
Liver mitochondrial membrane crosslinking and destruction in a rat model of Wilson disease.
Published in:
2011
By:
- Zischka, Hans;
- Lichtmannegger, Josef;
- Schmitt, Sabine;
- Jagemann, Nora;
- Schulz, Sabine;
- Wartini, Daniela;
- Jennen, Luise;
- Rust, Christian;
- Larochette, Nathanael;
- Galluzzi, Lorenzo;
- Chajes, Veronique;
- Bandow, Nathan;
- Valerie S. Gilles;
- DiSpirito, Alan A.;
- Esposito, Irene;
- Goettlicher, Martin;
- Summer, Karl H.;
- Kroemer, Guido;
- Jägemann, Nora;
- Gilles, Valérie S
Publication type:
journal article
RNA sensor-induced type I IFN prevents diabetes caused by a β cell-tropic virus in mice.
Published in:
2011
By:
- McCartney, Stephen A.;
- Vermi, William;
- Lonardi, Silvia;
- Rossini, Cristina;
- Otero, Karel;
- Calderon, Boris;
- Gilfillan, Susan;
- Diamond, Michael S.;
- Unanue, Emil R.;
- Colonna, Marco
Publication type:
journal article
Mouse and human neutrophils induce anaphylaxis.
Published in:
2011
By:
- Jänsson, Friederike;
- Mancardi, David A.;
- Kita, Yoshihiro;
- Karasuyama, Hajime;
- Iannascoli, Bruno;
- van Rooijen, Nico;
- Shimizu, Takao;
- Daëron, Marc;
- Bruhns, Pierre;
- Jönsson, Friederike;
- Daëron, Marc
Publication type:
journal article
Sequencing a mouse acute promyelocytic leukemia genome reveals genetic events relevant for disease progression.
Published in:
2011
By:
- Wartman, Lukas D.;
- Larson, David E.;
- Zhifu Xiang;
- Li Ding;
- Ken Chen;
- Ling Lin;
- Cahan, Patrick;
- Klco, Jeffery M.;
- Welch, John S.;
- Cheng Li;
- Payton, Jacqueline E.;
- Uy, Geoffrey L.;
- Varghese, Nobish;
- Ries, Rhonda E.;
- Hoock, Mieke;
- Koboldt, Daniel C.;
- McLellan, Michael D.;
- Schmidt, Heather;
- Fulton, Robert S.;
- Abbott, Rachel M.
Publication type:
journal article
Mycobacteria release active membrane vesicles that modulate immune responses in a TLR2-dependent manner in mice.
Published in:
2011
By:
- Prados-Rosales, Rafael;
- Baena, Andres;
- Martinez, Luis A.;
- Luque-Garcia, Jose;
- Kalscheuer, Rainer;
- Veeraraghavan, Usha;
- Camara, Carmen;
- Nosanchuk, Joshua D.;
- Besra, Gurdyal S.;
- Bing Chen;
- Jimenez, Juan;
- Glatman-Freedman, Aharona;
- Jacobs Jr., William R.;
- Porcelli, Steven A.;
- Casadevall, Arturo;
- Martinez, Luis R;
- Chen, Bing;
- Jacobs, William R Jr
Publication type:
journal article
Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow.
Published in:
2011
By:
- Shiozawa, Yusuke;
- Pedersen, Elisabeth A.;
- Havens, Aaron M.;
- Younghun Jung;
- Mishra, Anjali;
- Joseph, Jeena;
- Jin Koo Kim;
- Patel, Lalit R.;
- Chi Ying;
- Ziegler, Anne M.;
- Pienta, Michael J.;
- Junhui Song;
- Jingcheng Wang;
- Loberg, Robert D.;
- Krebsbach, Paul H.;
- Pienta, Kenneth J.;
- Taichman, Russell S.;
- Jung, Younghun;
- Kim, Jin Koo;
- Ying, Chi
Publication type:
journal article
NKp46 identifies an NKT cell subset susceptible to leukemic transformation in mouse and human.
Published in:
Journal of Clinical Investigation, 2011, v. 121, n. 4, p. 1456, doi. 10.1172/JCI43242
By:
- Jianhua Yu;
- Mitsui, Takeki;
- Min Wei;
- Hsiaoyin Mao;
- Butchar, Jonathan P.;
- Shah, Mithun Vinod;
- Jianying Zhang;
- Anjali Mishra;
- Alvarez-Breckenridge, Christopher;
- Xingluo Liu;
- Shujun Liu;
- Yokohama, Akihiko;
- Trotta, Rossana;
- Marcucci, Guido;
- Benson Jr., Don M.;
- Loughran Jr., Thomas P.;
- Tridandapani, Susheela;
- Caligiuri, Michael A.
Publication type:
Article
Genomic DNA damage and ATR-Chk1 signaling determine oncolytic adenoviral efficacy in human ovarian cancer cells.
Published in:
2011
By:
- Connell, Claire M.;
- Shibata, Atsushi;
- Tookman, Laura A.;
- Archibald, Kyra M.;
- Flak, Magdalena B.;
- Pirlo, Katrina J.;
- Lockley, Michelle;
- Wheatley, Sally P.;
- McNeish, Iain A.
Publication type:
journal article
Sleights of mind.
Published in:
2011
By:
- Kuhn, Gustav
Publication type:
Book Review
Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucoma.
Published in:
2011
By:
- Howell, Gareth R.;
- Macalinao, Danilo G.;
- Sousa, Gregory L.;
- Walden, Michael;
- Soto, Ileana;
- Kneeland, Stephen C.;
- Barbay, Jessica M.;
- King, Benjamin L.;
- Marchant, Jeffrey K.;
- Hibbs, Matthew;
- Stevens, Beth;
- Barres, Ben A.;
- Clark, Abbot F.;
- Libby, Richard T.;
- John, Simon W. M.
Publication type:
journal article
Rapid, reversible activation of AgRP neurons drives feeding behavior in mice.
Published in:
2011
By:
- Krashes, Michael J.;
- Shuichi Koda;
- ChianPing Ye;
- Rogan, Sarah C.;
- Adams, Andrew C.;
- Cusher, Daniel S.;
- Maratos-Flier, Eleftheria;
- Roth, Bryan L.;
- Lowell, Bradford B.;
- Koda, Shuichi;
- Ye, ChianPing
Publication type:
journal article
Abrogation of growth hormone secretion rescues fatty liver in mice with hepatocyte-specific deletion of JAK2.
Published in:
2011
By:
- Sos, Brandon C.;
- Charles Harris;
- Nordstrom, Sarah M.;
- Tran, Jennifer L.;
- Balázs, Mercedesz;
- Caplazi, Patrick;
- Febbraio, Maria;
- Applegate, Milana A. B.;
- Wagner, Kay-Uwe;
- Weiss, Ethan J.;
- Harris, Charles;
- Balázs, Mercedesz
Publication type:
journal article
Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans.
Published in:
2011
By:
- Rhee, Eugene P.;
- Susan Cheng;
- Larson, Martin G.;
- Geoffrey A. Walford;
- Lewis, Gregory D.;
- McCabe, Elizabeth;
- Yang, Elaine;
- Farrell, Laurie;
- Fox, Caroline S.;
- O'Donnell, Christopher J.;
- Carr, Steven A.;
- Vasan, Ramachandran S.;
- Florez, Jose C.;
- Clish, Clary B.;
- Wang, Thomas J.;
- Gerszten, Robert E.;
- Cheng, Susan;
- Walford, Geoffrey A
Publication type:
journal article
FOXO3 programs tumor-associated DCs to become tolerogenic in human and murine prostate cancer.
Published in:
2011
By:
- Watkins, Stephanie K.;
- Ziqiang Zhu;
- Riboldi, Elena;
- Shafer-Weaver, Kim A.;
- Stagliano, Katherine E. R.;
- Sklavos, Martha M.;
- Ambs, Stefan;
- Yagita, Hideo;
- Hurwitz, Arthur A.;
- Zhu, Ziqiang
Publication type:
journal article
The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice.
Published in:
2011
By:
- Castoldi, Mirco;
- Spasic, Maja Vujic;
- Altamura, Sandro;
- Elmén, Joacim;
- Lindow, Morten;
- Kiss, Judit;
- Stolte, Jens;
- Sparla, Richard;
- D'Alessandro, Lorenza A.;
- Klingmuller, Ursula;
- Fleming, Robert E.;
- Longerich, Thomas;
- Gröne, Hermann J.;
- Benes, Vladimir;
- Kauppinen, Sakari;
- Heritze, Matthias W.;
- Muckenthaler, Martina U.;
- Vujic Spasic, Maja;
- Elmén, Joacim;
- Klingmüller, Ursula
Publication type:
journal article
Brian Druker and Charles Sawyers receive the 2011 ASCI/Stanley J. Korsmeyer Award.
Published in:
2011
By:
- Claiborn, Kathryn
Publication type:
Biography
Enhancing discovery and saving money with MERIT.
Published in:
2011
By:
- Epstein, Jonathan A.
Publication type:
Editorial
Exploiting the mitochondrial unfolded protein response for cancer therapy in mice and human cells.
Published in:
2011
By:
- Siegelin, Markus D.;
- Dohi, Takehiko;
- Raskett, Christopher M.;
- Orlowski, Gregory M.;
- Powers, Christine M.;
- Gilbert, Candace A.;
- Ross, Alonzo H.;
- Plescia, Janet;
- Altieri, Dario C.
Publication type:
journal article
An activated mutant BRAF kinase domain is sufficient to induce pilocytic astrocytoma in mice.
Published in:
2011
By:
- Gronych, Jan;
- Korshunov, Andrey;
- Bageritz, Josephine;
- Milde, Till;
- Jugold, Manfred;
- Hambardzumyan, Dolores;
- Remke, Marc;
- Hartmann, Christian;
- Witt, Hendrik;
- Jones, David T. W.;
- Witt, Olaf;
- Heiland, Sabine;
- Bendszus, Martin;
- Holland, Eric C.;
- Pfister, Stefan;
- Lichter, Peter
Publication type:
journal article
Cop1 constitutively regulates c-Jun protein stability and functions as a tumor suppressor in mice.
Published in:
2011
By:
- Migliorini, Domenico;
- Bogaerts, Sven;
- Defever, Dieter;
- Vyas, Rajesh;
- Geertrui Denecker;
- Radaelli, Enrico;
- Zwolinska, Aleksandra;
- Depaepe, Vanessa;
- Hochepied, Tino;
- Skarnes, William C.;
- Marine, Jean-Christophe;
- Denecker, Geertrui
Publication type:
journal article
Upregulated stromal EGFR and vascular remodeling in mouse xenograft models of angiogenesis inhibitor-resistant human lung adenocarcinoma.
Published in:
2011
By:
- Cascone, Tina;
- Herynk, Matthew H.;
- Li Xu;
- Zhiqiang Du;
- Kadara, Humam;
- Nilsson, Monique B.;
- Oborn, Carol J.;
- Vun-Vong Park;
- Erez, Baruch;
- Jacoby, Jarg J.;
- Ju-Seog Lee;
- Lin, Heather V.;
- Ciardiello, Fortunato;
- Herbst, Roy S.;
- Langley, Robert R.;
- Heymach, John V.;
- Xu, Li;
- Du, Zhiqiang;
- Park, Yun-Yong;
- Jacoby, Jörg J
Publication type:
journal article
The telomerase inhibitor PinX1 is a major haploinsufficient tumor suppressor essential for chromosome stability in mice.
Published in:
Journal of Clinical Investigation, 2011, v. 121, n. 4, p. 1266, doi. 10.1172/JCI43452
By:
- Xiao Zhen Zhou;
- Pengyu Huang;
- Rong Shi;
- Tae Ho Lee;
- Gina Lu;
- Zhihong Zhang;
- Bronson, Roderick;
- Kun Ping Lu
Publication type:
Article
Good COP1 or bad COP1? In vivo veritas.
Published in:
2011
By:
- Wenyi Wei;
- Kaelin Jr., William G.
Publication type:
Opinion
Neutrophils give us a shock.
Published in:
2011
By:
- Lowell, Clifford A.
Publication type:
journal article
Finding a needle in a haystack: whole genome sequencing and mutation discovery in murine models.
Published in:
2011
By:
- Rampal, Raajit K.;
- Levine, Ross L.
Publication type:
journal article
Dietary nitrate, nitric oxide, and restenosis.
Published in:
2011
By:
- Cooke, John P.;
- Ghebremariam, Yohannes T.
Publication type:
journal article
Niche competition and cancer metastasis to bone.
Published in:
2011
By:
- Schuettpelz, Laura G.;
- Link, Daniel C.
Publication type:
journal article
Myocarditis: a defect in central immune tolerance?
Published in:
2011
By:
- Metzger, Todd C.;
- Anderson, Mark S.
Publication type:
journal article
Tolerogenic pDCs: spotlight on Foxo3.
Published in:
2011
By:
- Bronte, Vincenzo
Publication type:
journal article
The adaptive stroma joining the antiangiogenic resistance front.
Published in:
2011
By:
- Casanovas, Oriol
Publication type:
journal article
PinX1 the tail on the chromosome.
Published in:
2011
By:
- Johnson, F. Brad
Publication type:
journal article

Found: 52