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Genome-Wide CRISPR Screens Reveal ZATT as a Synthetic Lethal Target of TOP2-Poison Etoposide That Can Act in a TDP2-Independent Pathway.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 7, p. 6545, doi. 10.3390/ijms24076545
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- Article
BAGEL: a computational framework for identifying essential genes from pooled library screens.
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- BMC Bioinformatics, 2016, v. 17, p. 1, doi. 10.1186/s12859-016-1015-8
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- Article
HumanNet v2: human gene networks for disease research.
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- Nucleic Acids Research, 2019, v. 47, n. D1, p. D573, doi. 10.1093/nar/gky1126
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- Article
PICKLES: the database of pooled in-vitroCRISPR knockout library essentiality screens.
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- Nucleic Acids Research, 2018, v. 46, n. D1, p. D776, doi. 10.1093/nar/gkx993
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- Article
Discovery of putative tumor suppressors from CRISPR screens reveals rewired lipid metabolism in acute myeloid leukemia cells.
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- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26867-8
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- Article
Improved analysis of CRISPR fitness screens and reduced off-target effects with the BAGEL2 gene essentiality classifier.
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- Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-020-00809-3
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- Article
Scaling up the systematic hunt for mammalian genetic interactions.
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- Nature Methods, 2013, v. 10, n. 5, p. 397, doi. 10.1038/nmeth.2449
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- Article
Efficient gene knockout and genetic interaction screening using the in4mer CRISPR/Cas12a multiplex knockout platform.
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- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-47795-3
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- Article
Dynamic rewiring of biological activity across genotype and lineage revealed by context-dependent functional interactions.
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- Genome Biology, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s13059-022-02712-z
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- Article
Multiplex enCas12a screens detect functional buffering among paralogs otherwise masked in monogenic Cas9 knockout screens.
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- Genome Biology, 2020, v. 21, n. 1, p. N.PAG, doi. 10.1186/s13059-020-02173-2
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- Article
Human Cell Chips: Adapting DNA Microarray Spotting Technology to Cell-Based Imaging Assays.
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- PLoS ONE, 2009, v. 4, n. 10, p. 1, doi. 10.1371/journal.pone.0007088
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- Article
Pooled library screening with multiplexed Cpf1 library.
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- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10963-x
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- Article
Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens.
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- G3: Genes | Genomes | Genetics, 2017, v. 7, n. 8, p. 2719, doi. 10.1534/g3.117.041277
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- Article
Extensive mapping of an innate immune network with CRISPR.
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- Molecular Systems Biology, 2015, v. 11, n. 7, p. 1, doi. 10.15252/msb.20156373
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- Article
Measuring error rates in genomic perturbation screens: gold standards for human functional genomics.
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- Molecular Systems Biology, 2014, v. 10, n. 7, p. n/a, doi. 10.15252/msb.20145216
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- Article
A map of human protein interactions derived from co-expression of human mRNAs and their orthologs.
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- Molecular Systems Biology, 2008, v. 4, n. 1, p. 1, doi. 10.1038/msb.2008.19
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- Article
Common computational tools for analyzing CRISPR screens.
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- Emerging Topics in Life Sciences, 2021, v. 5, n. 6, p. 779, doi. 10.1042/ETLS20210222
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- Article
Recovering false negatives in CRISPR fitness screens with JLOE.
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- Nucleic Acids Research, 2023, v. 51, n. 4, p. 1637, doi. 10.1093/nar/gkad046
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- Article
PICKLES v3: the updated database of pooled in vitro CRISPR knockout library essentiality screens.
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- Nucleic Acids Research, 2023, v. 51, n. D1, p. D1117, doi. 10.1093/nar/gkac982
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- Article
HumanNet v3: an improved database of human gene networks for disease research.
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- Nucleic Acids Research, 2022, v. 50, n. D1, p. D632, doi. 10.1093/nar/gkab1048
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- Article
Genetic vulnerabilities upon inhibition of DNA damage response.
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- Nucleic Acids Research, 2021, v. 49, n. 14, p. 8214, doi. 10.1093/nar/gkab643
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A rapid in vitro methodology for simultaneous target discovery and antibody generation against functional cell subpopulations.
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- Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-018-37462-1
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- Article
Finding the active genes in deep RNA-seq gene expression studies.
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- BMC Genomics, 2013, v. 14, n. 1, p. 1, doi. 10.1186/1471-2164-14-778
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- Article
Optimal construction of a functional interaction network from pooled library CRISPR fitness screens.
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- BMC Bioinformatics, 2022, v. 22, n. 10, p. 1, doi. 10.1186/s12859-022-05078-y
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- Article
Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer.
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- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-17549-y
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- Article
Identifying chemogenetic interactions from CRISPR screens with drugZ.
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- Genome Medicine, 2019, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13073-019-0665-3
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- Article