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- Title
Two New Xanthones From Swertia atroviolacea and Their Anti-5 α-Reductase Activity.
- Authors
Xing, Huan-huan; Xiang, Neng-Jun; Liu, Li-Xuang; Yang, Guo-Rong; Shen, Yan-Fei; Yang, Yan; Zhou, Ling; Ma, Hang-Ying; Zhou, Min; Wu, Hai-Yan; Li, Gan-Peng; Hu, Qiu-Fen
- Abstract
Two new xanthones, atroxanthones A and B ( 1 and 2), together with four known xanthones ( 3-6), were isolated from the whole herb of Swertia atroviolacea. The structures of the metabolites were established on the basis of detailed spectroscopic analysis. Compounds 1 and 2 were evaluated for their anti-5α-reductase activity. The results revealed that 1 and 2 had weak activity with reductase inhibitions of 52.3 ± 2.5% and 42.9 ± 2.8%, respectively.
- Subjects
SWERTIA; CHEMICAL composition of plants; XANTHONE; REDUCTASES; METABOLITES; CHEMICAL structure; INHIBITION (Chemistry)
- Publication
Chemistry of Natural Compounds, 2017, Vol 53, Issue 6, p1052
- ISSN
0009-3130
- Publication type
Article
- DOI
10.1007/s10600-017-2199-5