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- Title
Clinical, hormonal and sonographic predictors of successful RU-486-induced abortions.
- Authors
Menashe, Yehezkel; Bider, David; Shalev, Josef; Pariente, Clara; Serr, David M.; Menashe, Y; Bider, D; Shalev, J; Pariente, C; Serr, D M
- Abstract
To evaluate which method, clinical, hormonal or sonographic, can be used as the best predictor of successful RU-486-induced abortions, 20 healthy women with fetal cardiac activity, between 6 and 9 weeks from the last menstrual period and desiring abortion, were studied. Fourteen women (70%) successfully aborted, and 6 (30%) failed to abort within 7 days following therapy. A small hematoma, seen as a localized detachment of the gestational sac, was observed in the decidua capsularis in women who aborted successfully. A significant decrease in plasma levels of estradiol and progesterone (p < 0.04) and significantly increased cortisol levels (p < 0.001) in the plasma of the 14 patients who aborted were noted by the 7th day following treatment. No significant changes were observed in the 6 nonaborting patients. In conclusion, the differences in the early sonographic findings may be helpful in the early prediction of successful RU-486 administration.
- Publication
Gynecologic & Obstetric Investigation, 1995, Vol 40, Issue 2, p108
- ISSN
0378-7346
- Publication type
journal article
- DOI
10.1159/000292316