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- Title
Association Study between DRD2 Genetic Polymorphisms and Schizophrenia in a Korean Population.
- Authors
Tae-Sung Kim; Seung-Min Cha; Seong-Keun Wang; Jeong-Lan Kim; Young-Ho Lee; Hye-In Choi; Ik-Seung Chee
- Abstract
Objectives This study was designed to investigate the association between the dopamine D2 receptor (DRD2) genetic polymorphism [TaqIB (rs17294542) and TaqID (rs1800498)] and patients with schizophrenia. MethodsZZTaqIB (rs17294542) and TaqID (rs1800498) polymorphism of the DRD2 gene were typed in 100 patients with schizophrenia and 109 normal controls. Results There were no statistical differences in genotype and allele distribution of TaqIB (rs17294542) and TaqID (rs1800498) genetic polymorphism between patients with schizophrenia and normal controls. Conclusions These results suggest that the TaqIB (rs17294542) and TaqID (rs1800498) polymorphisms of the DRD2 gene may not be associated with schizophrenia in the Korean population.
- Subjects
KOREA; GENETIC polymorphisms; SCHIZOPHRENIA; PEOPLE with schizophrenia; DOPAMINE receptors; ALLELES
- Publication
Korean Journal of Biological Psychiatry, 2012, Vol 19, Issue 1, p53
- ISSN
1225-8709
- Publication type
Article