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- Title
Long-term outcomes of magnetic resonance imaging-invisible endometrial cancer.
- Authors
Hyun-Jin Choi; Sunyoung Lee; Byung Kwan Park; Tae-Joong Kim; Chan Kyo Kim; Jung Jae Park; Chel Hun Choi; Yoo-Young Lee; Jeong-Won Lee; Duk-Soo Bae; Byoung-Gie Kim
- Abstract
Objective: Magnetic resonance imaging (MRI) is useful for staging endometrial cancer. The treatment and prognosis of MRI-invisible endometrial cancer remain unclear. The purpose of this study was to retrospectively evaluate the long-term outcomes of patients with MRIinvisible endometrial cancer. Methods: Between February 1995 and December 2011, we reviewed the medical records of 433 patients with endometrial cancer, which was staged IA on MRI. Of these patients, 89 had MRI-invisible cancer and 344 had MRI-visible cancer. Both cancers were treated with simple hysterectomy with or without lymph node dissection according to the surgeon's decision. Both cancers were compared regarding pathologic findings, recurrence rates, and survival rates. Results: The median sizes of MRI-invisible and MRI-visible cancers were 4 mm (0 to 40 mm) and 20 mm (0 to 89 mm), respectively (p<0.001). Myometrial invasion of these groups were detected in 20.2% (18/89) and 56.7% (195/344), respectively (p<0.001). Lymphadenectomy and follow-up imaging revealed no lymph node metastasis in patients with MRI-invisible cancers, while those revealed in 4.7% (16/344) of patients with MRI-visible cancers (p=0.052). The recurrence rates of MRI-invisible and MRI-visible cancers were 1.1% (1/89) and 7.8% (27/344), respectively (p=0.026). The recurrence-free survival rates of these groups were 98.9% (88/89) and 91.6% (315/344), respectively (p=0.022). Conclusion: MRI-invisible endometrial cancer can be treated with less invasive surgery because of its lower tumor burden and better prognosis. This cancer may not require lymphadenectomy because of no metastasis or recurrence in lymph nodes.
- Subjects
TREATMENT of endometrial cancer; MAGNETIC resonance imaging; CANCER prognosis; HEALTH outcome assessment; METASTASIS; CANCER relapse
- Publication
Journal of Gynecologic Oncology, 2016, Vol 27, Issue 4, p1
- ISSN
2005-0380
- Publication type
Article
- DOI
10.3802/jgo.2016.27.e38