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- Title
INTRAOPERATIVE COMPARISON BETWEEN ISOFLURANE AND NITROGLYCERIN FOR HYPOTENSIVE ANAESTHESIA.
- Authors
Sahoo, Nirod kumar; Rajsamant, Nagendra Kumar; Mohanty, Sujit Kumar; Mallick, Mrutyunjaya
- Abstract
Introduction All surgeries involve cutting of the blood vessels which will obviously result in bleeding. Deliberate hypotension is a method to produce a controlled and safe reduction in the intravascular pressure, while preserving organ perfusion. By enhancing the visualization of the surgical field, hypotension allows accurate delineation of lesions thereby causing fewer traumas to the delicate structures. Therefore intricate operations may be performed easily, exactly and therefore more successfully. Extensive surgical procedures are associated with considerable haemorrhage during and after surgery. The concept of intentionally decreasing arterial BP to hypotensive levels during surgery was first proposed by Cushing in 1917 for intracranial surgery and was introduced into clinical practice by Gardner in 1946. Since then, this technique has been variously named as controlled hypotension, Induced hypotension, deliberate hypotension and hypotensive anaesthesia. Deliberate hypotension is defined as the intentional reduction of the systemic perfusion pressure. Most studies define deliberate hypotension as reduction in systolic blood pressure (SBP) to 80-90mm Hg (30% decrease in the SBP from the baseline pressure). According to another definition, deliberate hypotension is a decrease in the mean arterial pressure (MAP) to 50-65 mm Hg in normotensive patients. Main purpose of hypotensive anaesthesia is to decrease intraoperative blood loss, thereby improving operating condition or decreasing the need for blood transfusions.
- Subjects
SYSTOLIC blood pressure; SURGICAL blood loss; ISOFLURANE; NITROGLYCERIN; ANESTHESIA
- Publication
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research), 2023, Vol 14, Issue 12, p462
- ISSN
0975-3583
- Publication type
Article