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- Title
TAKOTSUBO KARDIOMIOPATIJA.
- Authors
Adamović, Dragana; Mitov, Vladimir; Jolić, Aleksandar; Nikolić, Milan; Dimitrijević, Marko
- Abstract
Takotsubo cardiomyopathy is characterized by transient regional systolic dysfunction, which involves the tip and/ or middle part of the left ventricular chamber, in the absence of a significant coronary disease. Physical or mental stress has preceded. It occurs in 1.5 to 2.5% of patients with suspected acute coronary syndrome. The illness is more common in elderly females than males. Takotsubo cardiomyopathy is presented with chest pain, electrocardiographic changes and a minimal increase in cardiac-specific enzymes. The pathophysiological mechanism of Takotsubo cardiomyopathy is not yet completely explained. The 69-year-old patient, an American citizen, was admitted to the Department of Invasive Cardiology in Zajecar due to pain in the chests caused by intense stress, followed by ECG changes in the form of ST elevations from V1-3. At the first trastoracic echocardiographic examination, the areas of hypokinesia to the akinesia in the apical and medial segments of the left ventricle were described, and left ventricle ejection fraction EF was estimated to be 45%. Immediately after reception, selective angiography of coronary arteries was performed but angiographically significant stenosis was not observed. Clinical suspicion of Takotsubo cardiomyopathy was established. The patient was stable throughout the hospitalization, without any new symptoms. She was treated with angiotensin convertase inhibitor(ACEI), beta blocker, statin and acute coronary syndrome therapy. Cardiospecific enzymes were slightly increased as well as BNP levels. On repeated transthoracic echocardiographic examination finding was improved: hypokinesia of distal segments of the left ventricle, with left ventricular ballooning, and estimated EF 50-54% was registered.
- Publication
Timocki Medicinski Glasnik, 2018, Vol 43, Issue 2, p62
- ISSN
0350-2899
- Publication type
Article
- DOI
10.5937/tmg1802062a