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- Title
Late-onset myocardial infarction and autoimmune haemolytic anaemia in a COVID-19 patient without respiratory symptoms, concomitant with a paradoxical increase in inflammatory markers: a case report.
- Authors
Pelle, Maria Chiara; Tassone, Bruno; Ricchio, Marco; Mazzitelli, Maria; Davoli, Chiara; Procopio, Giada; Cancelliere, Anna; La Gamba, Valentina; Lio, Elena; Matera, Giovanni; Quirino, Angela; Barreca, Giorgio Settimo; Trecarichi, Enrico Maria; Torti, Carlo; IDTM UMG COVID-19 Group; Arrighi, Eugenio; Bertucci, Bernardo; Busceti, Maria Teresa; Carallo, Claudio; Costanzo, Francesco Saverio
- Abstract
<bold>Background: </bold>In December 2019, a new coronavirus (named severe acute respiratory syndrome coronavirus 2, SARS-CoV-2) spread from China, causing a pandemic in a very short time. The main clinical presentation of SARS-CoV-2 infection (COVID-19, coronavirus disease-2019) is pneumonia, but several cardiovascular complications may also occur (e.g., acute coronary syndromes, pulmonary embolism, stroke, arrhythmias, heart failure and cardiogenic shock). Direct or indirect mechanisms induced by SARS-CoV-2 could be implicated in the pathogenesis of these events.<bold>Case Presentation: </bold>We report herein the third case of COVID-19 autoimmune haemolytic anaemia (AIHA) reported so far, which occurredwithout any other possible explanations in a Caucasian patient. The patient also suffered from ST-elevation myocardial injury.<bold>Conclusions: </bold>Both complications occurred quite late after COVID-19 diagnosis and were probably precipitated by systemic inflammation, as indicated by a significant delayed increase in inflammatory markers, including interleukin-6 (IL-6).
- Subjects
CHINA; AUTOIMMUNE hemolytic anemia; MYOCARDIAL infarction; COVID-19; SYMPTOMS; SARS-CoV-2; ACUTE coronary syndrome
- Publication
Journal of Medical Case Reports, 2020, Vol 14, Issue 1, p1
- ISSN
1752-1947
- Publication type
Article
- DOI
10.1186/s13256-020-02595-3