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- Title
Nutritional therapy complications in children with ultra-short bowel syndrome include growth deficiency but not cholestasis.
- Authors
Olszewska, Katarzyna; Ksiazyk, Janusz; Kozlowski, Dariusz; Pajdowska, Magdalena; Janusz, Malgorzata; Jaworski, Maciej
- Abstract
<bold>Aim: </bold>Children with ultra-short bowel syndrome (USBS) have not been extensively studied to date because the condition is rare. The aim of the study was to assess the nutritional status of children with USBS receiving home parenteral nutrition, using citrulline serum concentration and cholestasis.<bold>Methods: </bold>We studied 17 patients with USBS, with a median age of 6.6 years and median duration of parenteral nutrition of 6.6 years. The study was carried out at The Children's Memorial Health Institute, Warsaw, from January 2014 to January 2015.<bold>Results: </bold>The median standard deviation score (SDS) was -1.2 for body mass according to chronological age, -1.72 according to height and -0.59 according to height for age. Patients requiring seven days per week parenteral nutrition had a citrulline concentration below 10 μmol/L. Decreased bone-mineral density was observed in 87% of the patients. Low values of 25-hydroxyvitamin D were found in 53% of the children. None of the patients had elevated conjugated bilirubin levels above 34.2 μmol/L.<bold>Conclusion: </bold>Children with USBS were growth deficient according to their chronological age, with frequent abnormal bone mineralisation and vitamin D deficiency. Children requiring parenteral nutrition seven days a week had citrulline concentrations below 10 μmol/L. Cholestasis was not seen.
- Subjects
DIET therapy; SHORT bowel syndrome; PARENTERAL feeding; CHOLESTASIS in children; STANDARD deviations
- Publication
Acta Paediatrica, 2018, Vol 107, Issue 6, p1088
- ISSN
0803-5253
- Publication type
journal article
- DOI
10.1111/apa.14260