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- Title
Addressing the burden of neonatal hyperbilirubinaemia in countries with significant glucose-6-phosphate dehydrogenase deficiency.
- Authors
Olusanya, Bolajoko O.; Emokpae, Abieyuwa A.; Zamora, Tara G.; Slusher, Tina M.
- Abstract
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an established worldwide risk factor for severe hyperbilirubinaemia. This literature review examined the pattern and management of severe hyperbilirubinaemia in low- and middle-income countries (LMICs) where G6PD deficiency was 10% or more and found that it was frequently associated with neonatal mortality and, or, neurodevelopmental disorders. Conclusion: Low- and middle-income countries need to pay urgent attention to G6PD deficiency to curtail the preventable burden of jaundice-related morbidity, mortality and disability.
- Subjects
GLUCOSE-6-phosphate dehydrogenase deficiency; HEMOLYTIC anemia; INBORN errors of metabolism; CONGENITAL hemolytic anemia; SICKLE cell anemia
- Publication
Acta Paediatrica, 2014, Vol 103, Issue 11, p1102
- ISSN
0803-5253
- Publication type
Article
- DOI
10.1111/apa.12735