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- Title
Relationship Between High Sensitivity C-reactive Protein to Albumin Ratio With Infarct-related Artery Patency in Patients With Non-ST-segment Elevation Myocardial Infarction.
- Authors
Özkan, Can; Karayiğit, Orhan
- Abstract
The C-reactive protein/albumin ratio (CAR) has recently emerged as a marker for poor prognosis or mortality in various patient groups. This study aimed to examine the relationship between serum CAR and infarct-related artery (IRA) patency in 700 consecutive non-ST-segment elevation myocardial infarction (NSTEMI) patients prior to percutaneous coronary intervention. The study population was separated into 2 different groups according to preprocedural IRA patency as assessed by the degree of Thrombolysis in Myocardial Infarction (TIMI) flow. As a result, occluded IRA was defined as TIMI grade 0-1, while patent IRA was defined as TIMI grade 2-3. High CAR (Odds Ratio: 3.153 (1.249-8.022); P <.001) was found to be an independent predictor of occluded IRA. Additionally, CAR was positively correlated with the SYNTAX score, neutrophil/lymphocyte ratio, and platelet/lymphocyte ratio; CAR was negatively correlated with left ventricular ejection fraction. The highest cut-off value of CAR predicting occluded IRA was found to be.18 with 68.3% sensitivity and 67.9% specificity. The area under the curve for CAR was.744 (95% CI:.706-.781) after the receiver-operating characteristic curve assessment.
- Subjects
PREDICTIVE tests; NON-ST elevated myocardial infarction; VENTRICULAR ejection fraction; RECEIVER operating characteristic curves; DESCRIPTIVE statistics; RETROSPECTIVE studies; CORONARY arteries; VASCULAR resistance; ODDS ratio; COMPARATIVE studies; CONFIDENCE intervals; C-reactive protein; SERUM albumin; BIOMARKERS; DISEASE complications
- Publication
Angiology, 2024, Vol 75, Issue 7, p682
- ISSN
0003-3197
- Publication type
Article
- DOI
10.1177/00033197231176983