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- Title
Use of Tilapia Skin as a Xenograft for Pediatric Burn Treatment: A Case Report.
- Authors
Costa, Bruno Almeida; Júnior, Edmar Maciel Lima; Filho, Manoel Odorico de Moraes; Fechine, Francisco Vagnaldo; Moraes, Maria Elisabete Amaral de; Júnior, Francisco Raimundo Silva; Soares, Maria Flaviane Araújo do Nascimento; Rocha, Marina Becker Sales; de Moraes Filho, Manoel Odorico; de Moraes, Maria Elisabete Amaral; do Nascimento Soares, Maria Flaviane Araújo; Lima Júnior, Edmar Maciel; Silva Júnior, Francisco Raimundo
- Abstract
Burns represent the fifth most common cause of nonfatal childhood injuries in the world. The Nile tilapia skin (Oreochromis niloticus) is widely available in Brazil and demonstrated, in previous studies, noninfectious microbiota, morphological structure similar to that of human skin, and good outcomes when used as a xenograft for treatment of experimental burns in rats. A 3-year-old boy was admitted to a burn treatment center in Fortaleza, Brazil, with scalds in the left side of the face, neck, anterior thorax, abdomen, and left arm. Involvement of 18% of total body surface area with superficial partial thickness burns was calculated. After local Institutional Review Board approval and written permission from the patient's legal caregiver were obtained, application of tilapia skin as an occlusive dressing was performed. Good adherence of tilapia skin to the wound bed was detected. The patient was discharged from the hospital with a total of 10 days required for the complete re-epithelialization of his superficial partial thickness burn. No adverse effects were noted. We believe that further studies conducted by our researchers will allow this innovative, low-cost, widely available and easy to apply biomaterial to firm itself as a relevant option in the therapeutic arsenal of pediatric burns, producing significant social and financial impact for the health system.
- Subjects
FORTALEZA (Brazil); BRAZIL; TILAPIA; PEDIATRIC therapy; CHEMICAL burns; NILE tilapia; HOSPITAL admission &; discharge; BODY surface area; TREATMENT for burns &; scalds; SKIN grafting; XENOGRAFTS; BURNS &; scalds; BURDEN of care; OCCLUSIVE surgical dressings; PSYCHOLOGICAL tests; FISHES; FAMILY relations; ANIMALS
- Publication
Journal of Burn Care & Research, 2019, p714
- ISSN
1559-047X
- Publication type
journal article
- DOI
10.1093/jbcr/irz085