We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
A one-pot method for the synthesis of phenylalkynyl-substituted terminal alkynes by deprotection/stannylation followed by a Migita-Kosugi-Stille coupling.
- Authors
Li-fen Peng; Bing-hao Wang; Ming Wang; Zi-long Tang; Yan-zi Jiang; Yin-chun Jiao; Xin-hua Xu
- Abstract
A practical one-pot approach for the synthesis of arylalkynyl-substituted terminal alkynes has been developed through a deprotection/ stannylation of a phenylethynyl phosphine oxide followed by Migita-Kosugi-Stille coupling, avoiding the longer synthetic route involving repeated deprotection/Sonogashira coupling. Other features of this approach include mild reaction conditions, excellent yields, facile isolation of products and wide functional group tolerance.
- Subjects
CHEMICAL reactions; COUPLING reactions (Chemistry); ALKYNES; ORGANIC compounds; CHEMICAL structure
- Publication
Journal of Chemical Research, 2018, Vol 42, Issue 5, p235
- ISSN
1747-5198
- Publication type
Article
- DOI
10.3184/174751918X15258743466204