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- Title
Minor Phospholipid Fractions in the Mechanism of Adaptation of Wild Rodents to Increased Radiation Background.
- Authors
Shishkina, L. N.; Kudyasheva, A. G.
- Abstract
The role of minor fractions of the liver phospholipids in the mechanism of adaptation of four species of wild rodents trapped in different years in the Chernobyl accident zone in areas with a dose rate of the external gamma radiation in 1987 from 0.02 to 200 mR/h to an increased radiation background is studied, depending on the radioresistance of the species. In the first year after the accident, an increase in the share of PL lysoforms and sphingomyelin involved in apoptosis and an increase in cardiolipin taking part in the interaction of DNA with the membrane were revealed. Within 5 years after the accident, there is an increase in the sum share of phosphatidylinositol and phosphatidylserine taking part in the transport of calcium ions and in the regulation of intracellular processes. Data obtained and the analysis of the literature allow us to conclude that changes in the proportion of minor fractions of PL in the liver of wild rodents living on territories with the increased radiation levels, causing adaptive rearrangements of cellular metabolism, were the basis for the formation of new subpopulations of rodents in these territories with a different from norm system of regulation of lipid peroxidation.
- Subjects
CHORNOBYL (Ukraine); BACKGROUND radiation; RODENTS; GAMMA rays; CALCIUM ions; CESIUM isotopes; PHOSPHATIDYLSERINES; RADIOACTIVE fallout
- Publication
Biology Bulletin, 2023, Vol 50, Issue 12, p3286
- ISSN
1062-3590
- Publication type
Article
- DOI
10.1134/S1062359023120208