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- Title
Perfusion Index-Bedside Diagnosis of Hemodynamically Significant Patent Ductus Arteriosus.
- Authors
Balla, Kalyan Chakravarthy; John, Vinu; P. N., Suman Rao; Varghese, Kiron; Rao Pn, Suman
- Abstract
<bold>Background: </bold>Patent ductus arteriosus (PDA) is a significant problem in preterm babies <34 weeks old. Echocardiogram (echo) is the gold standard for diagnosing PDA. Perfusion index (PI) using a pulse oximeter could aid in diagnosing a hemodynamically significant PDA (HsPDA).<bold>Objective: </bold>To evaluate the accuracy of delta-PI (ΔPI; pre-ductal - post-ductal PI) in diagnosing HsPDA in preterm babies <34 weeks old.<bold>Design: </bold>Prospective analytical cross-sectional (observational) study.<bold>Methods: </bold>Preterm infants <34 weeks old (n = 27) were enrolled in the study after parental consent. ΔPI was calculated on Days 1 and 3. Babies are categorized into two groups-HsPDA and no HsPDA based on echo on Day 3.<bold>Results: </bold>The mean gestational ages were 30.4 ± 1.9 (HsPDA) and 31.7 ± 1.6 weeks (no HsPDA), and birth weights were 1.23 ± 0.32 kg and 1.43 ± 0.34 kg, respectively (p > 0.05). Ten infants had HsPDA. The ΔPI values in Groups A and B differed significantly on Days 1 and 3 (Day 1: 1.06 ± 0.3 vs. 0.54 ± 0.2 and Day 3: 1.11 ± 0.15 vs. 0.57 ± 0.3). The area under the receiver operating characteristic curve was significant for ΔPI on Days 1 and 3. The ΔPI > 0.85 on Day 1 and > 0.95 on Day 3 had a sensitivity and specificity of 80% and 94% and 80% and 88.2%, respectively, for diagnosing HsPDA.<bold>Conclusion: </bold>ΔPI is a useful, simple parameter, which could help in the assessment of PDA in preterm babies.
- Subjects
DUCTUS arteriosus; GESTATIONAL age; PATENT ductus arteriosus; PREMATURE infants; ECHO; PATIENTS; BLOOD circulation; CLINICAL trials; ECHOCARDIOGRAPHY; HEMODYNAMICS; LONGITUDINAL method; OXIMETRY; PHYSICS; PREDICTIVE tests; CROSS-sectional method; RECEIVER operating characteristic curves; PHYSIOLOGY
- Publication
Journal of Tropical Pediatrics, 2016, Vol 62, Issue 4, p263
- ISSN
0142-6338
- Publication type
journal article
- DOI
10.1093/tropej/fmv086