We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
The Evaluation of Liver Steatosis with Transient Elastography in Metabolic Syndrome and the Relationship Between Serum Endorphin Levels.
- Authors
Çetin, Seher İrem; Beydoğan, Engin; Güzel, Savaş; Maviş, Osman; Böyük, Banu
- Abstract
Objective: Studies in recent times researching the correlation between serum endotrophin level and Type 2 DM have focused on the association of fatty liver with metabolic syndrome. This study aims to research the correlation between serum endotrophin levels, defined as a marker of metabolic dysregulation, with nonalcoholic fatty liver in metabolic syndrome patients, with increasing prevalence. Methods: Our prospective study included 40 patients (24 females and 16 males) with metabolic syndrome attending the internal medicine clinic and 20 healthy volunteers (ten females and ten males). Evaluation of patients in terms of liver steatosis used transabdominal ultrasonography with a Toshiba 500 Aplio brand model ultrasound device with 10 MHz convex probe with transient elastography method. Fatty Liver Index and Hepatic Steatosis Index (HSI) were calculated on the basis sample analyses. The endotrophin levels were studied with a Sunred enzyme-linked ımmunosorbent assay kit. Results: Endotrophin levels were found to be lower in the group with metabolic syndrome compared to the healthy group and results were statistically significant different (p<0.001). When the mean elastography results for the groups (in m/s and kPa) are compared, there were statistically significant differences found (p=0.001, p<0.001). There were statistically significant differences between HSI score with serum insulin levels and homeostasis model assessment results. Conclusion: In our study, a correlation was not found between endotrophin levels and fatty liver. Endotrophin is a parameter with newly discovered effects and is being researched for applicability and reliability in clinical practice.
- Subjects
TOSHIBA KK; METABOLIC syndrome; FATTY liver; ACOUSTIC radiation force impulse imaging; FATTY degeneration; ENZYME-linked immunosorbent assay; ELASTOGRAPHY; LIVER
- Publication
Southern Clinics of Istanbul Eurasia, 2021, Vol 32, Issue 1, p58
- ISSN
2587-0998
- Publication type
Article
- DOI
10.14744/scie.2020.03779