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- Title
Nano, micro particulate and cosmetic delivery systems of polylactic acid: A mini review.
- Authors
Abu Hajleh, Maha N.; AL‐Samydai, Ali; Al‐Dujaili, Emad A. S.
- Abstract
Background: Poly lactic acid and its copolymers are considered to be the preferred substrates for drug delivery devices. Poly lactic acid is a biocompatible, biodegradable and nontoxic polymer. It was approved by Food and Drug Administration and thought to be among the most attractive polymeric candidates intended for controlling drug delivery. It was utilized for the development of devices for the delivery of small molecules, proteins, genes, vaccines, anticancer drugs, and macromolecules. Objectives and methods: This manuscript lists the different techniques for synthesizing poly lactic acid‐based nano and microparticles such as emulsion‐based methods, precipitation‐based methods, direct compositing methods, in situ forming micro‐particles, and microfluidic technique. Conclusions: In addition, it describes the application and use of poly lactic acid in biomedical and cosmetic delivery systems.
- Subjects
UNITED States. Food &; Drug Administration; POLYLACTIC acid; DRUG delivery devices; SMALL molecules; COSMETIC dermatology; MEDICAL polymers; ANTINEOPLASTIC agents
- Publication
Journal of Cosmetic Dermatology, 2020, Vol 19, Issue 11, p2805
- ISSN
1473-2130
- Publication type
Article
- DOI
10.1111/jocd.13696