We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Cluster analysis of carbapenemase-producing organisms in Alberta using a geographic information system.
- Authors
Jamilano, Jeremy; Ye Shen; Ellison, Jennifer; Leal, Jenine
- Abstract
Background: The international emergence of carbapenemase-producing organisms (CPOs) among gram-negative bacteria represents a public health threat. In Canada, CPO rates have been increasing and there is growing concern of CPO reservoirs that may exist outside of hospital settings. The geographic patterns of CPOs were investigated in Alberta, Canada using geographic information systems and spatial analysis was performed to determine the presence of any spatial clusters of CPOs. Methods: Using multiple healthcare data sources, CPO case information identified in the community and healthcare settings were collected. The CPO cases were analyzed using spatial scan statistics to detect any CPO spatial clusters within the province of Alberta. The identified spatial clusters were stratified based on the collected healthcare data from the surveillance management system. Results: Spatial analysis confirmed two CPO spatial clusters, specifically within the municipalities of Edmonton and Calgary. The spatial cluster in southeast Edmonton had 27 CPO cases with a relative risk of 9.06 (p < .001). The spatial cluster in northeast Calgary had 22 CPO cases with a relative risk of 6.24 (p < .001). The NDM gene was the primary gene type in both spatial clusters and there was a higher proportion of cases that had previous history of travel outside of Alberta without healthcare exposure. The Serratia marcescens enzyme gene was observed to have the second highest proportion in all the CPO cases in the province, however, it was not well represented in either spatial cluster. Conclusions: The study confirmed spatial patterns of CPO distribution in Alberta. The findings can direct additional studies and may be used to develop community-specific interventions or strategies to prevent the transmission of CPO in Alberta.
- Subjects
ALBERTA; PUBLIC health surveillance; GEOGRAPHIC information systems; DATABASES; STATISTICS; STATISTICAL significance; MEDICAL information storage &; retrieval systems; CARBAPENEM-resistant bacteria; RETROSPECTIVE studies; PUBLIC health; SEVERITY of illness index; RISK assessment; DISEASE prevalence; DESCRIPTIVE statistics; GRAM-negative bacterial diseases; CLUSTER analysis (Statistics); DATA analysis; DATA analysis software
- Publication
Canadian Journal of Infection Control / Revue Canadienne de Prévention des Infections, 2023, p120
- ISSN
1183-5702
- Publication type
Article