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- Title
Letter the editor: serious methodological concerns about a recently published meta-analysis on oxygen therapy.
- Authors
Klitgaard, Thomas Lass; Schjørring, Olav Lilleholt; Nielsen, Frederik Mølgaard; Meyhoff, Christian Sylvest; Barbateskovic, Marija; Wetterslev, Jørn; Perner, Anders; Rasmussen, Bodil Steen
- Abstract
In a recent paper, Chen et al. report the findings of a systematic review with meta-analysis concerning conservative versus conventional oxygen therapy for critically ill patients. We wish to commend the authors for their interest in the matter. However, the authors appear to misquote findings, fail to report results for all specified analyses, do not identify all relevant trials, have post hoc changed the eligibility criteria, and have seemingly switched directions of effects in analyses of secondary outcomes. These issues have led to incorrect conclusions concerning the effects of targeted oxygen therapy in critically ill patients.
- Subjects
OXYGEN therapy; CRITICALLY ill; SECONDARY analysis; CRITICAL care medicine
- Publication
Journal of Intensive Care, 2021, Vol 9, Issue 1, p1
- ISSN
2052-0492
- Publication type
Letter
- DOI
10.1186/s40560-021-00573-5