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- Title
Lymphocyte subsets in term and significantly preterm UK infants in the first year of life analysed by single platform flow cytometry.
- Authors
Berrington, J. E.; Barge, D.; Fenton, A. C.; Cant, A. J.; Spickett, G. P.
- Abstract
This observational study describes the ranges observed for lymphocyte subsets for significantly preterm infants (<32 weeks) in the first year of life, measured by single platform flow cytometry and compared to identically determined subsets in term infants. After ethical approval 39 term and 28 preterm infants had lymphocyte subset analysis before and after their primary immunization series. Median values with 5th and 95th percentiles of absolute counts and percentages are presented for total lymphocytes, T cells, NK cells, B cells, cytotoxic T cells, helper T cells, dual positive T cells, activated T cells, activated T helper cells (including T regulatory cells), pan memory T cells, pan naïve T cells, memory helper T cells, naïve helper T cells and the T helper/suppressor ratio. The lymphocyte profile of the preterm infants differed from that of the term infants.
- Subjects
LYMPHOCYTES; PREMATURE infants; FLOW cytometry; IMMUNIZATION; T cells; B cells
- Publication
Clinical & Experimental Immunology, 2005, Vol 140, Issue 2, p289
- ISSN
0009-9104
- Publication type
Article
- DOI
10.1111/j.1365-2249.2005.02767.x