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Corrigendum: An orally available small molecule that targets soluble TNF to deliver anti-TNF biologic-like efficacy in rheumatoid arthritis.
Published in:
Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1479557
By:
- Vugler, Alexander;
- O’connell, James;
- Nguyen, Mai Anh;
- Weitz, Dietmar;
- Leeuw, Thomas;
- Hickford, Elizabeth;
- Verbitsky, Alexander;
- Xiaoyou Ying;
- Rehberg, Markus;
- Carrington, Bruce;
- Merriman, Mark;
- Moss, Andrew;
- Nicolas, Jean-Marie;
- Stanley, Phil;
- Wright, Sara;
- Bourne, Tim;
- Foricher, Yann;
- Zhaoning Zhu;
- Brookings, Daniel;
- Horsley, Helen
Publication type:
Article
An orally available small molecule that targets soluble TNF to deliver anti-TNF biologic-like efficacy in rheumatoid arthritis Updated.
Published in:
Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2022.1037983
By:
- Vugler, Alexander;
- O’Connell, James;
- Nguyen, Mai Anh;
- Weitz, Dietmar;
- Leeuw, Thomas;
- Hickford, Elizabeth;
- Verbitsky, Alexander;
- Xiaoyou Ying;
- Rehberg, Markus;
- Carrington, Bruce;
- Merriman, Mark;
- Moss, Andrew;
- Nicholas, Jean-Marie;
- Stanley, Phil;
- Wright, Sara;
- Bourne, Tim;
- Foricher, Yann;
- Zhaoning Zhu;
- Brookings, Daniel;
- Horsley, Helen
Publication type:
Article
Corrigendum: An orally available small molecule that targets soluble TNF to deliver anti-TNF biologic-like efficacy in rheumatoid arthritis.
Published in:
Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1479557
By:
- Vugler, Alexander;
- O’connell, James;
- Nguyen, Mai Anh;
- Weitz, Dietmar;
- Leeuw, Thomas;
- Hickford, Elizabeth;
- Verbitsky, Alexander;
- Xiaoyou Ying;
- Rehberg, Markus;
- Carrington, Bruce;
- Merriman, Mark;
- Moss, Andrew;
- Nicolas, Jean-Marie;
- Stanley, Phil;
- Wright, Sara;
- Bourne, Tim;
- Foricher, Yann;
- Zhaoning Zhu;
- Brookings, Daniel;
- Horsley, Helen
Publication type:
Article
An orally available small molecule that targets soluble TNF to deliver anti-TNF biologic-like efficacy in rheumatoid arthritis.
Published in:
Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2022.1037983
By:
- Vugler, Alexander;
- O’Connell, James;
- Nguyen, Mai Anh;
- Weitz, Dietmar;
- Leeuw, Thomas;
- Hickford, Elizabeth;
- Verbitsky, Alexander;
- Xiaoyou Ying;
- Rehberg, Markus;
- Carrington, Bruce;
- Merriman, Mark;
- Moss, Andrew;
- Nicholas, Jean-Marie;
- Stanley, Phil;
- Wright, Sara;
- Bourne, Tim;
- Foricher, Yann;
- Zhaoning Zhu;
- Brookings, Daniel;
- Horsley, Helen
Publication type:
Article
An orally available small molecule that targets soluble TNF to deliver anti-TNF biologic-like efficacy in rheumatoid arthritis.
Published in:
Frontiers in Pharmacology, 2022, v. 13, p. 01, doi. 10.3389/fphar.2022.1037983
By:
- Vugler, Alexander;
- O'Connell, James;
- Nguyen, Mai Anh;
- Weitz, Dietmar;
- Leeuw, Thomas;
- Hickford, Elizabeth;
- Verbitsky, Alexander;
- Xiaoyou Ying;
- Rehberg, Markus;
- Carrington, Bruce;
- Merriman, Mark;
- Moss, Andrew;
- Nicholas, Jean-Marie;
- Stanley, Phil;
- Wright, Sara;
- Bourne, Tim;
- Foricher, Yann;
- Brookings, Daniel;
- Horsley, Helen;
- Herrmann, Matthias
Publication type:
Article
Efficacy of an Inhaled IL-13 Antibody Fragment in a Model of Chronic Asthma.
Published in:
2018
By:
- Lightwood, Daniel;
- Tservistas, Markus;
- Zehentleitner, Monique;
- Sarkar, Kaushik;
- Turner, Alison;
- Bracher, Marguerite;
- Smith, Bryan;
- Lamour, Sabrina;
- Bourne, Tim;
- Shaw, Stevan;
- Gozzard, Neil;
- Palframan, Roger T
Publication type:
journal article
Differential roles of CTP synthetases CTPS1 and CTPS2 in cell proliferation.
Published in:
Life Science Alliance, 2023, v. 6, n. 9, p. 1, doi. 10.26508/lsa.202302066
By:
- Minet, Norbert;
- Boschat, Anne-Claire;
- Lane, Rebecca;
- Laughton, David;
- Beer, Philip;
- Asnagli, Hélène;
- Soudais, Claire;
- Bourne, Tim;
- Fischer, Alain;
- Martin, Emmanuel;
- Latour, Sylvain
Publication type:
Article
Collagen II antibody-induced arthritis in Tg1278TNFko mice: optimization of a novel model to assess treatments targeting human TNFα in rheumatoid arthritis.
Published in:
2014
By:
- Moore, Adrian Richard;
- Allden, Sarah;
- Bourne, Tim;
- Denis, Maria C;
- Kranidioti, Ksanthi;
- Okoye, Remi;
- Sotsios, Yannis;
- Stencel, Zofia;
- Vugler, Alexander;
- Watt, Gillian;
- Shaw, Stevan
Publication type:
journal article
The Use of Surrogate Antibodies to Evaluate the Developmental and Reproductive Toxicity Potential of an Anti-TNFα PEGylated Fab′ Monoclonal Antibody.
Published in:
Toxicological Sciences, 2011, v. 122, n. 1, p. 170, doi. 10.1093/toxsci/kfr083
By:
- Wakefield, Ian;
- Stephens, Sue;
- Foulkes, Roly;
- Nesbitt, Andrew;
- Bourne, Tim
Publication type:
Article
A PEGylated Fabâ€² Fragment against Tumor Necrosis Factor for the Treatment of Crohn Disease: Exploring a New Mechanism of Action.
Published in:
BioDrugs, 2008, v. 22, n. 5, p. 331, doi. 10.2165/00063030-200822050-00005
By:
- Bourne, Tim;
- Fossati, Gianluca;
- Nesbitt, Andrew
Publication type:
Article
Structural insights into the disruption of TNF-TNFR1 signalling by small molecules stabilising a distorted TNF.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20828-3
By:
- McMillan, David;
- Martinez-Fleites, Carlos;
- Porter, John;
- Fox, David;
- Davis, Rachel;
- Mori, Prashant;
- Ceska, Tom;
- Carrington, Bruce;
- Lawson, Alastair;
- Bourne, Tim;
- O'Connell, James
Publication type:
Article
A conformation-selective monoclonal antibody against a small molecule-stabilised signalling-deficient form of TNF.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20825-6
By:
- Lightwood, Daniel J.;
- Munro, Rebecca J.;
- Porter, John;
- McMillan, David;
- Carrington, Bruce;
- Turner, Alison;
- Scott-Tucker, Anthony;
- Hickford, Elizabeth S.;
- Schmidt, Antje;
- Fox III, David;
- Maloney, Alison;
- Ceska, Tom;
- Bourne, Tim;
- O'Connell, James;
- Lawson, Alastair D. G.
Publication type:
Article
Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-13616-1
By:
- O'Connell, James;
- Porter, John;
- Kroeplien, Boris;
- Norman, Tim;
- Rapecki, Stephen;
- Davis, Rachel;
- McMillan, David;
- Arakaki, Tracy;
- Burgin, Alex;
- Fox III, David;
- Ceska, Tom;
- Lecomte, Fabien;
- Maloney, Alison;
- Vugler, Alex;
- Carrington, Bruce;
- Cossins, Benjamin P;
- Bourne, Tim;
- Lawson, Alastair
Publication type:
Article

Found: 13