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- Title
Aspergillus Niger Tiegh: An Endophyte from Gymnema Sylvestre for its Antihyperglycemic Potential.
- Authors
Vidyasagar, G. M.; S. G., Roopa; Ahmed, MD. Liyakat; Babanagare, Shankaravva; M. K., Sangeeta; Vasantkumar, Ambika
- Abstract
Traditional medicinal plant Gymnema sylvestre is used to cure many diseases and its availability in nature is very rare. In the present research, as an alternate to the host plant, fungal endophyte from leaves of G. sylvestre was isolated and based on morphological and molecular characterization the isolate was identified as Aspergillus niger Tiegh. The ethyl acetate extract of the fungus was further employed for qualitative and quantitative analysis of secondary metabolite, revealed presence of saponin, tannin, flavonoids, glycosides, phenol and alkaloid. The oral glucose tolerance test in fungal ethyl acetate extract (250mg/kg body weight) treated Albino mice has shown reduced level of blood glucose compared to the negative control group, whereas compared with standard drug no significant reduction recorded.
- Subjects
PHYTOCHEMICALS; ASPERGILLUS niger; GLUCOSE tolerance tests; TANNINS; BLOOD sugar; HOST plants; ETHYL acetate; BODY weight
- Publication
Journal of Plant Science Research, 2021, Vol 37, Issue 1, p167
- ISSN
0970-2539
- Publication type
Article
- DOI
10.32381/JPSR.2021.37.01.20