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- Title
Electroencephalogram (EEG) Duration Needed to Detect Abnormalities in Angelman Syndrome: Is 1 Hour of Overnight Recording Sufficient?
- Authors
Robinson, Althea A.; Goldman, Suzanne; Barnes, Gregory; Goodpaster, Luke; Malow, Beth A.
- Abstract
Approximately, 90% of patients with Angelman syndrome present with epileptic seizures. Obtaining an electroencephalogram (EEG) with sleep improves the chances of detecting ictal, interictal, and benign abnormal rhythms in Angelman syndrome. However, electroencephalograms, even when obtained during sleep, can be challenging in this population because of tactile sensitivities as well as anxiety related to a novel environment. We tested the hypothesis that 1 hour of sleep on an electroencephalogram would provide as much information as an entire night of electroencephalogram recording, yet more than a routine electroencephalogram conducted during the day. Overnight polysomnograms were collected in 14 children with Angelman syndrome seen at Vanderbilt University. All patients who obtained sleep within the first hour of the overnight electroencephalogram had interictal discharges recorded. Our results show that when sleep is obtained, a 1-hour electroencephalogram yields just as much information as recording an entire night.
- Subjects
ELECTROENCEPHALOGRAPHY; ANGELMAN syndrome; HUMAN chromosome 15 abnormalities; EPILEPSY; VANDERBILT University
- Publication
Journal of Child Neurology, 2015, Vol 30, Issue 1, p58
- ISSN
0883-0738
- Publication type
Article
- DOI
10.1177/0883073814530498