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- Title
PTSA‐Catalyzed [3+2] Cycloaddition of in Situ Generated 3‐Ylidene Oxindoles with Coumarin‐Based N‐Phenyl Enamine Derivatives.
- Authors
Yadav, Anoop; Dahiya, Pooja; Rawat, Megha; Peddinti, Rama Krishna
- Abstract
Brønsted acid mediated [3+2] cycloaddition of coumarin‐based enamines with 3‐ylidene oxindoles generated in situ from 3‐hydroxy‐3‐aroylmethyl oxindoles enabled the synthesis of polyheterocyclic compounds with a pyrrolocoumarin core structure in a highly regioselective manner. The synthetic procedure is highly efficient and metal‐free, and no chromatographic purification of the products is required. The chromenopyrrole derivatives bearing an oxindole moiety formed as rapidly interconverting rotamers.
- Subjects
OXINDOLES; RING formation (Chemistry); BRONSTED acids; CONFORMATIONAL isomers; ENAMINES
- Publication
European Journal of Organic Chemistry, 2024, Vol 27, Issue 10, p1
- ISSN
1434-193X
- Publication type
Article
- DOI
10.1002/ejoc.202301310