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- Title
Comparing the area under the curve and peak height methods in the calculation of FLT3‐ITD allelic ratio.
- Authors
Di Ciaccio, Pietro; Kearney, Anabel; Ling, Silvia
- Abstract
In the article, the authors discuss how to calculate the fms-like tyrosine kinase 3 gene (FLT3-ITD) in patients with acute myeloid leukaemia (AML). Also cited are the association of FLT3-ITD mutations with higher relapse rates and inferior survival, and other topics like allogeneic stem cell transplantation (ASCT) as AML treatment and the effective threshold of allelic ratio in defining FLT3-ITD.
- Subjects
ALLELES; DNA; GENETIC mutation; POLYMERASE chain reaction; RISK assessment; TRANSFERASES; ACUTE myeloid leukemia; STATISTICAL models; DISEASE risk factors
- Publication
International Journal of Laboratory Hematology, 2020, Vol 42, Issue 5, pe234
- ISSN
1751-5521
- Publication type
Article
- DOI
10.1111/ijlh.13263