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- Title
Perceived Significance of Isolated HBcAb in Patients with HIV: A Survey of Practitioners.
- Authors
Thomas-Gosain, Neena; Adeyemi, Oluwatoyin M.
- Abstract
The prevalence of the isolated hepatitis B core Ab phenotype (hepatitis B surface antigen negative [HBsAg−] hepatitis B surface antibody negative [HBsAb−], and hepatitis B core antibody positive [HBcAb+] is particularly high among human HIV-positive patients. Controversy exists regarding both the significance of this phenotype and the risk of progressive liver disease as well as the need for hepatitis B vaccination in this population. A survey of 40 HIV primary care providers (PCPs) at an urban outpatient HIV clinic was conducted in 2005 regarding these two issues and a summary of the findings are presented in this report. Seventy-eight percent thought that these patients' infection had resolved and were immune, half thought they were at risk for progressive liver disease, and 6 (15%) routinely administered hepatitis B vaccine to patients with this phenotype. The wide variety in attitudes and practices among providers in a single clinic suggests the need for further research and development of management guidelines in this group of patients.
- Subjects
HEPATITIS B; HIV-positive persons; HIV infections; VIRAL hepatitis; VACCINATION; PRIMARY care; PREVENTION of communicable diseases; PATIENTS
- Publication
AIDS Patient Care & STDs, 2007, Vol 21, Issue 6, p385
- ISSN
1087-2914
- Publication type
Article
- DOI
10.1089/apc.2006.0083