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- Title
Lymphoma of the orbit masquerading as Tolosa-Hunt syndrome.
- Authors
Shazly, Tarek A.; Mitchell, Ellen B.; Bonhomme, Gabrielle R.; Schuman, Joel S.
- Abstract
Background: Tolosa-Hunt syndrome is a rare clinical syndrome characterized by painful ophthalmoplegia and ipsilateral cranial neuropathies. It is caused by an inflammatory process of unknown etiology. Case presentation: We present a case of a 77-year-old white man with history of Waldenstrom's macroglobulinemia transforming to large B-cell lymphoma who presented to a community physician complaining of 4 months of isolated right retro-orbital pain and later with diplopia, ptosis, 6th nerve and pupil-sparing partial 3rd nerve palsies as well as progressive neurological findings. His clinical course was complicated by debilitating neurological symptoms and multiple hospitalizations leading to a delay in diagnosis caused by incomplete initial workup. Conclusion: This case is a reminder that lymphoproliferative disorders often mimic other neurologic disorders and that Tolosa-Hunt is a rare diagnosis that must be considered a diagnosis of exclusion.
- Subjects
TOLOSA-Hunt syndrome; EYE paralysis; WALDENSTROM'S macroglobulinemia; CAVERNOUS sinus; MAGNETIC resonance imaging
- Publication
BMC Ophthalmology, 2015, Vol 15, Issue 1, p1
- ISSN
1471-2415
- Publication type
Case Study
- DOI
10.1186/s12886-015-0037-8