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- Title
Women with elevated blood pressure and stage 1 hypertension are at high risk for preeclampsia. A retrospective study at a tertiary facility in Japan.
- Authors
Shindo, Ryosuke; Aoki, Shigeru; Nakanishi, Sayuri; Obata, Soichiro; Miyagi, Etsuko
- Abstract
Aim: In 2017, the American College of Cardiology (ACC) re‐defined hypertension (HT) as follows: elevated blood pressure (EBP), systolic blood pressure (SBP) 120–129 mmHg and diastolic blood pressure (DBP) <80 mmHg; stage 1 HT, SBP 130–139 mmHg or DBP 80–89 mmHg; and stage 2 HT: SBP ≥140 mmHg or DBP ≥90 mmHg. It is well known that women with stage 2 HT are at higher risk of preeclampsia and have poorer pregnancy and delivery outcomes. While there are few reports on the risk in women with EBP and stage 1 HT, and none from Japan. This study aimed to determine whether women in Japan with EBP and stage 1 HT are at risk of preeclampsia. Methods: In this single‐center retrospective study conducted in Japan, subjects were classified into stage 2 HT, stage 1 HT, EBP, and normal groups based on blood pressure measurements at the time of the first visit before 20 weeks of gestation. Women with a diagnosis of hypertension made before pregnancy were classified into the stage 2 HT group. We compared pregnancy and delivery outcomes, such as preeclampsia, between groups. Results: A total of 5129 cases (normal, n = 4283; EBP, n = 427; stage 1 HT, n = 303; stage 2 HT, n = 116) were included. Preeclampsia incidence rates were 2.7%, 5.6%, 10.6%, and 21.6%, respectively. The adjusted OR (95% CI) for preeclampsia incidence were 2.90 (1.81–4.66), 5.90 (3.87–9.20), and 13.80 (7.97–24.0), respectively. Conclusions: Women with EBP and stage 1 HT are at high risk of preeclampsia, similar to those with stage 2 HT.
- Subjects
UNITED States; JAPAN; HYPERTENSION epidemiology; BLOOD pressure; HYPERTENSION in pregnancy; CARDIOLOGY; CONFIDENCE intervals; TERTIARY care; RETROSPECTIVE studies; DISEASE incidence; PREECLAMPSIA; RISK assessment; PREGNANCY outcomes; COMPARATIVE studies; DESCRIPTIVE statistics; ODDS ratio; WOMEN'S health; DISEASE complications
- Publication
Journal of Obstetrics & Gynaecology Research, 2024, Vol 50, Issue 3, p366
- ISSN
1341-8076
- Publication type
Article
- DOI
10.1111/jog.15852