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Die Hauptprotease von SARS‐CoV‐2 als Zielstruktur: Von der Etablierung eines Hochdurchsatz‐Screenings zum Design maßgeschneiderter Inhibitoren.
Published in:
Angewandte Chemie, 2021, v. 133, n. 18, p. 10515, doi. 10.1002/ange.202016961
By:
- Breidenbach, Julian;
- Lemke, Carina;
- Pillaiyar, Thanigaimalai;
- Schäkel, Laura;
- Al Hamwi, Ghazl;
- Diett, Miriam;
- Gedschold, Robin;
- Geiger, Nina;
- Lopez, Vittoria;
- Mirza, Salahuddin;
- Namasivayam, Vigneshwaran;
- Schiedel, Anke C.;
- Sylvester, Katharina;
- Thimm, Dominik;
- Vielmuth, Christin;
- Phuong Vu, Lan;
- Zyulina, Maria;
- Bodem, Jochen;
- Gütschow, Michael;
- Müller, Christa E.
Publication type:
Article
Design, Synthesis and Biological Evaluation of Highly Potent Simplified Archazolids.
Published in:
ChemMedChem, 2020, v. 15, n. 14, p. 1348, doi. 10.1002/cmdc.202000154
By:
- Rivière, Solenne;
- Vielmuth, Christin;
- Ennenbach, Christiane;
- Abdelrahman, Aliaa;
- Lemke, Carina;
- Gütschow, Michael;
- Müller, Christa E.;
- Menche, Dirk
Publication type:
Article
Xanthine–Dopamine Hybrid Molecules as Multitarget Drugs with Potential for the Treatment of Neurodegenerative Diseases.
Published in:
Biomolecules (2218-273X), 2023, v. 13, n. 7, p. 1079, doi. 10.3390/biom13071079
By:
- Załuski, Michał;
- Karcz, Tadeusz;
- Drabczyńska, Anna;
- Vielmuth, Christin;
- Olejarz-Maciej, Agnieszka;
- Głuch-Lutwin, Monika;
- Mordyl, Barbara;
- Siwek, Agata;
- Satała, Grzegorz;
- Müller, Christa E.;
- Kieć-Kononowicz, Katarzyna
Publication type:
Article
Synthesis of Novel Pyrido[3,2- e][1,2,4]triazolo[1,5- c]pyrimidine Derivatives: Potent and Selective Adenosine A3 Receptor Antagonists.
Published in:
Archiv der Pharmazie, 2013, v. 346, n. 10, p. 699, doi. 10.1002/ardp.201300003
By:
- Banda, Veeraswamy;
- Chandrasekaran, Balakumar;
- Köse, Meryem;
- Vielmuth, Christin;
- Müller, Christa E.;
- Chavva, Kurumurthy;
- Gautham, Santhosh Kumar;
- Pillalamarri, Sambasivarao;
- Mylavaram, Raghuprasad;
- Akkinepally, Raghuramarao;
- Pamulaparthy, Shanthanrao;
- Banda, Narsaiah
Publication type:
Article
Irreversible Antagonists for the Adenosine A 2B Receptor †.
Published in:
Molecules, 2022, v. 27, n. 12, p. 3792, doi. 10.3390/molecules27123792
By:
- Temirak, Ahmed;
- Schlegel, Jonathan G.;
- Voss, Jan H.;
- Vaaßen, Victoria J.;
- Vielmuth, Christin;
- Claff, Tobias;
- Müller, Christa E.
Publication type:
Article
Innentitelbild: Eine einzige stabilisierende Punktmutation ermöglicht hochaufgelöste Co‐Kristallstrukturen des Adenosin‐A2A‐Rezeptors mit Preladenant‐Konjugaten (Angew. Chem. 22/2022).
Published in:
Angewandte Chemie, 2022, v. 134, n. 22, p. 1, doi. 10.1002/ange.202115545
By:
- Claff, Tobias;
- Klapschinski, Tim A.;
- Tiruttani Subhramanyam, Udaya K.;
- Vaaßen, Victoria J.;
- Schlegel, Jonathan G.;
- Vielmuth, Christin;
- Voß, Jan H.;
- Labahn, Jörg;
- Müller, Christa E.
Publication type:
Article
Eine einzige stabilisierende Punktmutation ermöglicht hochaufgelöste Co‐Kristallstrukturen des Adenosin‐A2A‐Rezeptors mit Preladenant‐Konjugaten.
Published in:
Angewandte Chemie, 2022, v. 134, n. 22, p. 1, doi. 10.1002/ange.202115545
By:
- Claff, Tobias;
- Klapschinski, Tim A.;
- Tiruttani Subhramanyam, Udaya K.;
- Vaaßen, Victoria J.;
- Schlegel, Jonathan G.;
- Vielmuth, Christin;
- Voß, Jan H.;
- Labahn, Jörg;
- Müller, Christa E.
Publication type:
Article
Inside Cover: Single Stabilizing Point Mutation Enables High‐Resolution Co‐Crystal Structures of the Adenosine A2A Receptor with Preladenant Conjugates (Angew. Chem. Int. Ed. 22/2022).
Published in:
Angewandte Chemie International Edition, 2022, v. 61, n. 22, p. 1, doi. 10.1002/anie.202115545
By:
- Claff, Tobias;
- Klapschinski, Tim A.;
- Tiruttani Subhramanyam, Udaya K.;
- Vaaßen, Victoria J.;
- Schlegel, Jonathan G.;
- Vielmuth, Christin;
- Voß, Jan H.;
- Labahn, Jörg;
- Müller, Christa E.
Publication type:
Article
Single Stabilizing Point Mutation Enables High‐Resolution Co‐Crystal Structures of the Adenosine A2A Receptor with Preladenant Conjugates.
Published in:
Angewandte Chemie International Edition, 2022, v. 61, n. 22, p. 1, doi. 10.1002/anie.202115545
By:
- Claff, Tobias;
- Klapschinski, Tim A.;
- Tiruttani Subhramanyam, Udaya K.;
- Vaaßen, Victoria J.;
- Schlegel, Jonathan G.;
- Vielmuth, Christin;
- Voß, Jan H.;
- Labahn, Jörg;
- Müller, Christa E.
Publication type:
Article
Targeting the Main Protease of SARS‐CoV‐2: From the Establishment of High Throughput Screening to the Design of Tailored Inhibitors.
Published in:
Angewandte Chemie International Edition, 2021, v. 60, n. 18, p. 10423, doi. 10.1002/anie.202016961
By:
- Breidenbach, Julian;
- Lemke, Carina;
- Pillaiyar, Thanigaimalai;
- Schäkel, Laura;
- Al Hamwi, Ghazl;
- Diett, Miriam;
- Gedschold, Robin;
- Geiger, Nina;
- Lopez, Vittoria;
- Mirza, Salahuddin;
- Namasivayam, Vigneshwaran;
- Schiedel, Anke C.;
- Sylvester, Katharina;
- Thimm, Dominik;
- Vielmuth, Christin;
- Phuong Vu, Lan;
- Zyulina, Maria;
- Bodem, Jochen;
- Gütschow, Michael;
- Müller, Christa E.
Publication type:
Article
Anti-Inflammatory Activities of 8-Benzylaminoxanthines Showing High Adenosine A 2A and Dual A 1 /A 2A Receptor Affinity.
Published in:
International Journal of Molecular Sciences, 2023, v. 24, n. 18, p. 13707, doi. 10.3390/ijms241813707
By:
- Załuski, Michał;
- Łażewska, Dorota;
- Jaśko, Piotr;
- Honkisz-Orzechowska, Ewelina;
- Kuder, Kamil J.;
- Brockmann, Andreas;
- Latacz, Gniewomir;
- Zygmunt, Małgorzata;
- Kaleta, Maria;
- Greser, Beril Anita;
- Olejarz-Maciej, Agnieszka;
- Jastrzębska-Więsek, Magdalena;
- Vielmuth, Christin;
- Müller, Christa E.;
- Kieć-Kononowicz, Katarzyna
Publication type:
Article

Found: 11

Die Hauptprotease von SARS‐CoV‐2 als Zielstruktur: Von der Etablierung eines Hochdurchsatz‐Screenings zum Design maßgeschneiderter Inhibitoren.

Design, Synthesis and Biological Evaluation of Highly Potent Simplified Archazolids.

Xanthine–Dopamine Hybrid Molecules as Multitarget Drugs with Potential for the Treatment of Neurodegenerative Diseases.

Synthesis of Novel Pyrido[3,2- e][1,2,4]triazolo[1,5- c]pyrimidine Derivatives: Potent and Selective Adenosine A<sub>3</sub> Receptor Antagonists.

Irreversible Antagonists for the Adenosine A 2B Receptor †.

Innentitelbild: Eine einzige stabilisierende Punktmutation ermöglicht hochaufgelöste Co‐Kristallstrukturen des Adenosin‐A<sub>2A</sub>‐Rezeptors mit Preladenant‐Konjugaten (Angew. Chem. 22/2022).

Eine einzige stabilisierende Punktmutation ermöglicht hochaufgelöste Co‐Kristallstrukturen des Adenosin‐A<sub>2A</sub>‐Rezeptors mit Preladenant‐Konjugaten.

Inside Cover: Single Stabilizing Point Mutation Enables High‐Resolution Co‐Crystal Structures of the Adenosine A<sub>2A</sub> Receptor with Preladenant Conjugates (Angew. Chem. Int. Ed. 22/2022).

Single Stabilizing Point Mutation Enables High‐Resolution Co‐Crystal Structures of the Adenosine A<sub>2A</sub> Receptor with Preladenant Conjugates.

Targeting the Main Protease of SARS‐CoV‐2: From the Establishment of High Throughput Screening to the Design of Tailored Inhibitors.

Anti-Inflammatory Activities of 8-Benzylaminoxanthines Showing High Adenosine A 2A and Dual A 1 /A 2A Receptor Affinity.