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- Title
International Hidradenitis Suppurativa Severity Scoring System (IHS4) as a holistic measure of hidradenitis suppurativa disease severity compared with Hurley staging: A post hoc analysis of the SUNRISE and SUNSHINE phase 3 trials of secukinumab.
- Authors
Zouboulis, Christos C.; Prens, Errol P.; Sayed, Christopher J.; Molina‐Leyva, Alejandro; Bettoli, Vincenzo; Romanelli, Marco; Szepietowski, Jacek C.; Martinez, Angela Llobet; Kasparek, Torben; Lobach, Iryna; Wozniak, Magdalena B.; Ortmann, Christine‐Elke; Thomas, Nicolas; Bachhuber, Teresa; Ravichandran, Shoba; Tzellos, Thrasyvoulos
- Abstract
The article explores the International Hidradenitis Suppurativa Severity Scoring System (IHS4) as a more comprehensive tool for assessing the severity of hidradenitis suppurativa (HS) compared to the commonly used Hurley staging. The IHS4 takes into account different lesion types and assigns them different weights to dynamically assess the severity of HS. The study analyzed data from two phase 3 trials of secukinumab and found that the IHS4 was able to categorize patients with moderate to severe HS more accurately than Hurley staging. The findings suggest that the IHS4 may be a valuable tool for evaluating HS severity in clinical practice.
- Subjects
HIDRADENITIS suppurativa; CLINICAL trials; SUNSHINE; HYPERHIDROSIS; SUNBURN
- Publication
Journal of the European Academy of Dermatology & Venereology, 2024, Vol 38, Issue 6, pe496
- ISSN
0926-9959
- Publication type
Article
- DOI
10.1111/jdv.19681