We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Erythema chronicum migrans: an electron-microscopic study.
- Authors
Van Mierlo, P.; Jacob, W.; Dockx, P.
- Abstract
Spirochaetal organisms are found in skin specimens obtained by biopsy from a erythema chronicum migrans lesion. The histological picture shows a logical localization of a lymphohistiocytic cell infiltrate: deep dermal in the central papule and superficial in the erythematous border. The electron-microscopic characteristics of the micro-organisms in these specimens (regular waving appearance with coils every 0.8-1.2 microns, oblique striation of periplasmatic fibrils, cross-section of 0.3 micron, membranes) correspond to the spiral-like structure of Borreliae isolated from blood. The Borreliae seem to move freely through the matrix of the dermis and are not phagocytized. This brings on the typical clinical picture of the centrifugally spreading erythematous band.
- Subjects
LYME disease diagnosis; ANIMAL experimentation; COMPARATIVE studies; ELECTRON microscopy; GRAM-negative bacteria; LYME disease; RESEARCH methodology; EVALUATION research
- Publication
Dermatology (10188665), 1993, Vol 186, Issue 4, p306
- ISSN
1018-8665
- Publication type
journal article
- DOI
10.1159/000247384