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- Title
Anaphylactic shock in pregnancy: a mini-review.
- Authors
Simionescu, Anca Angela; Stãnescu, Ana Maria Alexandra; Danciu, Bianca Mihaela; Vieru, Mariana
- Abstract
Anaphylactic shock is a severe, acute, generalized, hypersensitivity reaction that appears rarely during pregnancy, but which has significant adverse outcomes on the pregnant woman and the fetus due to hypotension. Herein we present a mini-review about the clinical diagnosis and management in pregnancy, based on cases described in literature. While its etiology is diverse, the most common cases of anaphylactic shock are represented by the administration of antibiotics, especially those for the prophylaxis of group B streptococcal infection, being followed, in the frequency order, by the anesthetic drugs. The maternal consequences of anaphylactic shock are various, besides hypotension, its manifestations being cutaneous, digestive, cardiovascular or respiratory. The fetal implications may include fetal bradycardia, ischemic hypoxic encephalopathy or even death. Adrenaline intramuscularly injected into the vastus lateralis of the quadriceps (anterolateral thigh) is the first-line treatment of anaphylaxis, therefore it should be rapidly available for pregnant women with potential risk of anaphylaxis. Serum tryptase is the only available validated biomarker for anaphylaxis.
- Subjects
ANAPHYLAXIS; HYPOTENSION in pregnancy; FETAL pathophysiology; STREPTOCOCCUS agalactiae; BACTERIAL disease treatment; ANTIBIOTICS
- Publication
Obstetrică şi Ginecologie, 2021, Vol 69, Issue 3, p134
- ISSN
1220-5532
- Publication type
Article
- DOI
10.26416/obsgin.69.3.2021.5555